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SR3335

SR3335 Structure
SR3335 structure
CAS No.
293753-05-6
Chemical Name:
SR3335
Synonyms
ML-176;SR3335;SR3335;ML176;ML-176;SR-3335;ML-176;SR 3335;SR-3335;ML176;ML 176;SR3335;ML-176;SR 3335;SR-3335;ML176;ML 176;SR 3335 (This product is only available in Japan.);N-[4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl]thiophene-2-sulfonamide;N-[4-[2,2,2-Trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-2-thiophenesulfonamide;2-Thiophenesulfonamide, N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-
CBNumber:
CB12628427
Molecular Formula:
C13H9F6NO3S2
Molecular Weight:
405.3358792
MDL Number:
MFCD02724814
MOL File:
293753-05-6.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:19
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SR3335 Properties

storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility insoluble in H2O; ≥87.4 mg/mL in EtOH; ≥88.8 mg/mL in DMSO
form solid

SR3335 price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML2820 SR3335 ≥98% (HPLC) 293753-05-6 5MG $94.2 2024-03-01 Buy
Sigma-Aldrich SML2820 SR3335 ≥98% (HPLC) 293753-05-6 25MG $381 2024-03-01 Buy
Cayman Chemical 12072 SR 3335 ≥95% 293753-05-6 1mg $32 2024-03-01 Buy
Cayman Chemical 12072 SR 3335 ≥95% 293753-05-6 5mg $106 2024-03-01 Buy
Cayman Chemical 12072 SR 3335 ≥95% 293753-05-6 10mg $186 2024-03-01 Buy
Product number Packaging Price Buy
SML2820 5MG $94.2 Buy
SML2820 25MG $381 Buy
12072 1mg $32 Buy
12072 5mg $106 Buy
12072 10mg $186 Buy

SR3335 Chemical Properties,Uses,Production

Description

The retinoic acid receptor-related receptors (RORs) are orphan nuclear receptors with diverse putative roles. SR 3335 is a selective inverse agonist of RORα, competitively inhibiting the binding of 25-hydroxycholesterol to the ligand binding domain (Ki = 220 nM) and inhibiting constitutive transactivation activity (IC50 = 480 nM). It is without effect on RORβ, RORγ, farnesoid X receptor, or liver X receptor α. SR 3335 evokes RORα-dependent effects both in vitro and in vivo, altering gene expression as well as gluconeogenesis.

Definition

ChEBI: N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-2-thiophenesulfonamide is a sulfonamide.

target

RORα

SR3335 synthesis

16629-19-9
722-92-9
293753-05-6
Synthesis of SR3335 from 2-Thiophenesulfonyl chloride and 4-(HEXAFLUORO-2-HYDROXYISOPROPYL)ANILINE

SR3335 Preparation Products And Raw materials

Raw materials

4-(HEXAFLUORO-2-HYDROXYISOPROPYL)ANILINE 2-Thiophenesulfonyl chloride Aniline

Preparation Products

SR3335 Suppliers

Global( 75)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32686 60
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8474 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+undefined18621343501 product@acmec-e.com China 33350 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131980 58
Dalian Meilun Biotech Co., Ltd. 0411-62910999 13889544652 sales@meilune.com China 4662 58
Supplier Advantage
career henan chemical co
58
ATK CHEMICAL COMPANY LIMITED 		60
BOC Sciences 		58
InvivoChem 		58
TargetMol Chemicals Inc. 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Shanghai Acmec Biochemical Technology Co., Ltd. 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
Dalian Meilun Biotech Co., Ltd. 58

View Lastest Price from SR3335 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SR3335 pictures 2019-12-23 SR3335
293753-05-6
 US $9.80 / KG 1g 99% 100kg Career Henan Chemical Co
  • SR3335 pictures
  • SR3335
    293753-05-6
  • US $9.80 / KG
  • 99%
  • Career Henan Chemical Co

SR3335 Spectrum

SR3335(293753-05-6)1HNMR
SR3335 SR3335,Thiophene-2-sulfonic acid [4-(2,2,2-trifluoro-1-hydroxy-1-trifluoroMethyl-ethyl)-phenyl]-aMide ML-176 N-[4-[2,2,2-Trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-2-thiophenesulfonamide hiophene-2-sulfonic acid [4-(2,2,2-trifluoro-1-hydroxy-1-trifluoroMethyl-ethyl)-phenyl]-aMide ML-176;SR-3335 SR3335;ML-176;SR 3335;SR-3335;ML176;ML 176 SR3335;ML176 SR 3335 (This product is only available in Japan.) Thiophene-2-sulfonic acid [4-(2,2,2-trifluoro-1-hydroxy-1-trifluoroMethyl-ethyl)-phenyl]-aMide ML-176;SR 3335;SR-3335;ML176;ML 176 2-Thiophenesulfonamide, N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]- N-[4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl]thiophene-2-sulfonamide 293753-05-6 C13H9F6NO3S2