Thioproperazine
- CAS No.
- 316-81-4
- Chemical Name:
- Thioproperazine
- Synonyms
- Vontil;Megeptil;Mazeptyl;Majeptyl;Cephalmin;Sulfenazin;hioproperazine;thioproperazine;N'-(4-chlorophenyl)-N,N-dimethylcarbamimidic acid methyl ester;N,N-Dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine-2-sulfonamide
- CBNumber:
- CB3912908
- Molecular Formula:
- C22H30N4O2S2
- Molecular Weight:
- 446.63
- MDL Number:
- MFCD00867741
- MOL File:
- 316-81-4.mol
- MSDS File:
- SDS
| Melting point | 140° |
|---|---|
| Boiling point | 612.2±65.0 °C(Predicted) |
| Density | 1.1476 (rough estimate) |
| refractive index | 1.6200 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 7.65±0.10(Predicted) |
| FDA UNII | YJ050AQ56X |
| NIST Chemistry Reference | Thioproperazine(316-81-4) |
| ATC code | N05AB08 |
Thioproperazine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PH003261 | N,N-dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine-2-sulfonamide AldrichCPR | 316-81-4 | 1MG | $172 | 2023-06-20 | Buy |
| Crysdot | CD11146489 | Thioproperazine 97% | 316-81-4 | 100mg | $416 | 2021-12-16 | Buy |
| Crysdot | CD11146489 | Thioproperazine 97% | 316-81-4 | 250mg | $665 | 2021-12-16 | Buy |
| Crysdot | CD11146489 | Thioproperazine 97% | 316-81-4 | 1g | $1664 | 2021-12-16 | Buy |
Thioproperazine Chemical Properties,Uses,Production
Originator
Majeptil,Specia,France,1960
Definition
ChEBI: A phenothiazine derivative in which the phenothiazine tricycle has a dimethylaminosulfonyl substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at N-10.
Manufacturing Process
A solution of 3-dimethylsulfamoylphenthiazine (5 g) in anhydrous xylene (100 cc) is heated under reflux for 1 hour with sodamide (0.67 g). 3-(4-methyl-1- piperazinyl)-1-chloropropane (3.2 g) in solution in anhydrous xylene (20 cc) is added and the mixture heated under reflux for 5 hours. After treatment of the reaction products, a crude oily base (2.5 g) is obtained after treatment. By the addition of a solution of fumaric acid in ethanol to an ethanolic solution of the base, 3-dimethylsulfamoyl-10-(3-41-methyl-11-piperazinylpropyl)- phenthiazinediacid fumarate (2.6 g) is obtained, melting point 182°C. The base recrystallized from ethyl acetate melts at about 140°C.
Therapeutic Function
Neuroleptic, Antiemetic
Thioproperazine Preparation Products And Raw materials
Thioproperazine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-18789408387 | 1057@dideu.com | China | 2713 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 9020 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33350 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | sales@capotchem.com | China | 18217 | 66 |
| ShangHai Movin Pharmaceutical Co., Ltd. | 13681854265 | info@moenpharm.com | China | 511 | 55 |
View Lastest Price from Thioproperazine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-05-22 | Thioproperazine
316-81-4
|
US $1.00 / G | 1G | 98% | 100G | Shaanxi Dideu Medichem Co. Ltd |
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- Thioproperazine
316-81-4
- US $1.00 / G
- 98%
- Shaanxi Dideu Medichem Co. Ltd