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ChemicalBook >> CAS DataBase List >>Apremilast

Apremilast suppliers

ApreMilast

CAS:
608141-41-9
MF:
C22H24N2O7S
MW:
460.5

Properties

Melting point:
152-156°C
Boiling point:
741.3±60.0 °C(Predicted)
Density 
1.381
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
pka
14.01±0.20(Predicted)
form 
Solid
color 
White to Pale Yellow
InChIKey
IMOZEMNVLZVGJZ-QGZVFWFLSA-N
SMILES
C(NC1=CC=CC2=C1C(=O)N([C@@H](C1=CC=C(OC)C(OCC)=C1)CS(C)(=O)=O)C2=O)(=O)C

Safety Information

Symbol(GHS) 
GHS hazard pictogramsGHS hazard pictograms
GHS08,GHS07
Signal word 
Warning
Hazard statements 
H302-H361
Precautionary statements 
P201-P202-P281-P308+P313-P405-P501-P264-P270-P301+P312-P330-P501

Use

Apremilast (Otezla) was approved by the FDA on March 21, 2014 for the treatment of adult patients with active psoriatic arthritis. Apremilast is a member of a new class of oral small molecule inhibitors of the phosphosphodiesterase 4 (PDE4) enzyme. When PDE4 is inhibited in immune cells, it results in elevation of intracellular cyclic adenosine monophosphate (cAMP) levels, which can regulate inflammatory mediators. The current clinical data indicate that apremilast is an effective and well tolerated option for the management of psoriasis and PsA in adults.

379 supplier list of "ApreMilast"

  • Product Name:Apremilast (CC-10004)
  • Products Intro:Purity: 0.98 | Package: 100mg;1g;500g | CustNote: Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Pharmaceutical intermediates,raw materials,small molecule inhibitors,food additives,Biochemical reagents

$0.00/ 25KG

  • Product Name:Apremilast
  • Products Intro:Purity: 99% | Package: 25KG
  • Company Type: Service provider
  • Country/Region: CHINA
  • Main Products: carbomer,lead acetate,phenylacetamide,Xylazine,Xylazine hcl

$0.00/ 25Kg/Bag

  • Product Name:Apremilast
  • Products Intro:Purity: 99% up|Package: 25Kg/Bag;0.00;USD
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: APIs,pharmaceutical intermediates,health and food supplements,cosmetic raw materials,herbal extracts

$0.00/ 1g

  • Product Name:Apremilast
  • Products Intro:Purity: 98% HPLC | Package: 1g
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Inosine pranobex,Probenecid,Sodium Ceftiofur,3-O-Ethyl-L-ascorbic acid,benzhexol hydrochloride

$0.00-0.00 / 1KG

  • Product Name:Apremilast
  • Products Intro:Purity: 99.0% min | Package: 1kg;|10kg;|100kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: 2-Chloromalonaldehyde,(R)-5,7-difluorochroman-4-ol,Cyclobutanecarboxylic acid,(Bromomethyl)cyclobutane,5-Amino-4-imidazolecarboxamide

$200.00-1.00 / 1KG

  • Product Name:Apremilast
  • Products Intro:Purity: 99%, 99.5% Sublimated | Package: 1KG;200USD|100KG;1USD
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Chemical raw materials,Organic raw materials,Petrochemicals,Chemical reagents,Intermediates
  • Product Name:Apremilast
  • Products Intro:Purity: 99.7% | Package: 1kg;10USD
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Sodium lignosulfonate,phenylglycine,5337-93-9,141-78-6,Dispersant MF
Apremilast
  • Product Name:Apremilast
  • Products Intro:Purity: 99% | Package: 1kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:Apremilast
  • Products Intro:Purity: 98% Min. | Package: 1G;1KG;100KG
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: 1159983-30-8,89466-59-1,149739-51-5,104901-79-3,10541-83-0
  • Product Name:Apremilast
  • Products Intro:Purity: 99% | Package: 25KG;5KG;1KG
  • Company Type: Trader
  • Country/Region: CHINA
You can find Apremilast suppliers, manufacturers, and distributors from countries such as China, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

ApreMilast Related Search:

1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl) ethanone3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamideApremilast3-acetamidophthalic acidPazopanibAvanafilNintedanibTrametinibPLX4032[[p-(2-methoxyethyl)phenoxy]methyl]oxirane (S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine N-acetyl-L-leucine salt1,3-Dioxo-2-isoindolineaceticacidApremilast Impurity EApremilast Impurity HApremilast Impurity F
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