VTX-2337
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- $33 - $1800
- Product name: VTX-2337
- CAS: 926927-61-9
- MF: C28H34N4O2
- MW: 458.6
- EINECS:
- MDL Number:MFCD28044318
- Synonyms:Obicetrapib;2-amino-n,n-dipropyl-8-[4-(pyrrolidine-1-carbonyl)phenyl]-3h-1-benzazepine-4-carboxamide;VTX-2337;VTX 378;Motolimod;2-amino-N,N-dipropyl-8-(4-(pyrrolidine-1-carbonyl)phenyl)-3H-benzo[b]azepine-4-carboxamide;Motolimod(VTX-2337);VTX 2337;VTX2337;VTX-378
16 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number2129CW
- Product descriptionMotolimod
- Packaging1mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number22952
- Product descriptionMotolimod ≥98%
- Packaging1mg
- Price$33
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22952
- Product descriptionMotolimod ≥98%
- Packaging5mg
- Price$112
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22952
- Product descriptionMotolimod ≥98%
- Packaging10mg
- Price$208
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22952
- Product descriptionMotolimod ≥98%
- Packaging25mg
- Price$396
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM255809
- Product description2-Amino-N,N-dipropyl-8-(4-(pyrrolidine-1-carbonyl)phenyl)-3H-benzo[b]azepine-4-carboxamide 98%
- Packaging50mg
- Price$458
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4309
- Product descriptionMotolimod 98.58%
- Packaging5mg
- Price$204
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4309
- Product descriptionMotolimod 98.58%
- Packaging10mg
- Price$324
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4309
- Product descriptionMotolimod 98.58%
- Packaging25mg
- Price$588
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4309
- Product descriptionMotolimod 98.58%
- Packaging50mg
- Price$840
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000225
- Product descriptionMotolimod 98+%
- Packaging10mg
- Price$256
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000225
- Product descriptionMotolimod 98+%
- Packaging25mg
- Price$453
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000225
- Product descriptionMotolimod 98+%
- Packaging50mg
- Price$718
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8815
- Product descriptionMotolimod(VTX-2337) >98%
- Packaging100mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8815
- Product descriptionMotolimod(VTX-2337) >98%
- Packaging250mg
- Price$900
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8815
- Product descriptionMotolimod(VTX-2337) >98%
- Packaging1g
- Price$1800
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2129CW | Motolimod | 1mg | $135 | 2021-12-16 | Buy |
| Cayman Chemical | 22952 | Motolimod ≥98% | 1mg | $33 | 2024-03-01 | Buy |
| Cayman Chemical | 22952 | Motolimod ≥98% | 5mg | $112 | 2024-03-01 | Buy |
| Cayman Chemical | 22952 | Motolimod ≥98% | 10mg | $208 | 2024-03-01 | Buy |
| Cayman Chemical | 22952 | Motolimod ≥98% | 25mg | $396 | 2024-03-01 | Buy |
| Chemenu | CM255809 | 2-Amino-N,N-dipropyl-8-(4-(pyrrolidine-1-carbonyl)phenyl)-3H-benzo[b]azepine-4-carboxamide 98% | 50mg | $458 | 2021-12-16 | Buy |
| ChemScene | CS-4309 | Motolimod 98.58% | 5mg | $204 | 2021-12-16 | Buy |
| ChemScene | CS-4309 | Motolimod 98.58% | 10mg | $324 | 2021-12-16 | Buy |
| ChemScene | CS-4309 | Motolimod 98.58% | 25mg | $588 | 2021-12-16 | Buy |
| ChemScene | CS-4309 | Motolimod 98.58% | 50mg | $840 | 2021-12-16 | Buy |
| Crysdot | CD31000225 | Motolimod 98+% | 10mg | $256 | 2021-12-16 | Buy |
| Crysdot | CD31000225 | Motolimod 98+% | 25mg | $453 | 2021-12-16 | Buy |
| Crysdot | CD31000225 | Motolimod 98+% | 50mg | $718 | 2021-12-16 | Buy |
| DC Chemicals | DC8815 | Motolimod(VTX-2337) >98% | 100mg | $500 | 2021-12-16 | Buy |
| DC Chemicals | DC8815 | Motolimod(VTX-2337) >98% | 250mg | $900 | 2021-12-16 | Buy |
| DC Chemicals | DC8815 | Motolimod(VTX-2337) >98% | 1g | $1800 | 2021-12-16 | Buy |
Properties
Boiling point :718.7±70.0 °C(Predicted)
Density :1.19±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml)
form :solid
pka :2.47±0.40(Predicted)
color :Off-white or pale yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Density :1.19±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml)
form :solid
pka :2.47±0.40(Predicted)
color :Off-white or pale yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Description
Motolimod is an agonist of toll-like receptor 8 (TLR8). It increases the production of TNF-α and IL-12 in human peripheral blood mononuclear cells (PBMCs; EC50s = 140 and 120 nM, respectively), monocytes, and myeloid dendritic cells. Motolimod also increases IFN-γ production in natural killer (NK) cells and increases cytolysis in K562 NK cell-sensitive leukemia cells when used at concentrations of 167 and 500 nM for 48 hours. It increases plasma levels of a group of human cytokines, including IL-6, IL-12p70, TNF-α, MCP-1, and MIP-1β, in NOD-scid IL2rynull (NSG) mice reconstituted with human immune system (NSG-HIS) when administered at doses of 1.5 and 15 mg/m2. Motolimod, when used in combination with pegylated liposomal doxorubicin (PLD), reduces tumor growth and increases tumor infiltration of monocytes and T cells in an ovarian cancer NSG-HIS mouse model.Related product price
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