| | 20554-84-1 Basic information More.. |
| Product Name: | Parthenolide | | Synonyms: | [1aR-(1aR*,4E,7aS*,10aS*,-10bR*)]-2,3-6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one;(1aR,4E,7aS,10aS,10bS)-2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one;4,5α-Epoxy-6β-hydroxygermacra-1(10),11(13)-dien-12-oic acid γ-lactone;4,5alpha-epoxy-6beta-hydroxy-germacra-1(10),11(13)-dien-12-oic acid gamma-lactone;Germacra-1(10),11(13)-dien-12-oic acid, 4,5-alpha-epoxy-6-beta-hydroxy-, gamma-lactone;Parthenolide;Parthenolide ((-)-Parthenolide);PartheNAlide | | CAS: | 20554-84-1 | | MF: | C15H20O3 | | MW: | 248.32 | | EINECS: | 692-532-0 | | Mol File: | 20554-84-1.mol |  |
Use
Parthenolide is a sesquiterpene lactone from the plant feverfew (T. parthenium). It inhibits the growth of the promastigote form of L. amazonensis (IC50 = 3.6 μg/ml). Parthenolide also induces apoptosis in cancer cells, at least in part by inhibiting NF-κB- and STAT-mediated anti-apoptotic gene transcription. This compound has also been shown to block inflammation by inhibiting signaling through NF-κB. Inhibition of NF-κB by parthenolide can be achieved by direct binding of the pattern recognition receptor NOD2 by parthenolide.
- Parthenolide
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- US $10.00 / kg
- 2024-06-04
- CAS:20554-84-1
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 100tons
- Parthenolide
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- US $0.00-0.00 / kg
- 2024-05-20
- CAS:20554-84-1
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 50000kg
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20554-84-1
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