Company Name: |
TargetMol Chemicals Inc.
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Tel: |
15002134094 |
Email: |
marketing@targetmol.com |
Products Intro: |
Product Name:KRAS G12C inhibitor 28 CAS:2649004-88-4 Purity:详情请点击官网 Package:1 mg
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| Pyrido[2,3-d]pyrimidin-2(1H)-one, 1-[4-(dimethylphosphinyl)-2-methyl-6-(1-methylethyl)phenyl]-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]- Basic information |
| Pyrido[2,3-d]pyrimidin-2(1H)-one, 1-[4-(dimethylphosphinyl)-2-methyl-6-(1-methylethyl)phenyl]-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]- Chemical Properties |
Boiling point | 826.8±75.0 °C(Predicted) | density | 1.34±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | pka | 6.52±0.35(Predicted) |
| Pyrido[2,3-d]pyrimidin-2(1H)-one, 1-[4-(dimethylphosphinyl)-2-methyl-6-(1-methylethyl)phenyl]-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]- Usage And Synthesis |
Description | KRAS G12C inhibitor 28 is a KRAS G12C inhibitor with an IC50 of 57 nM. KRAS G12C inhibitor 28 has antitumor effects (WO2021113595A1; Example 1)[1]. |
| Pyrido[2,3-d]pyrimidin-2(1H)-one, 1-[4-(dimethylphosphinyl)-2-methyl-6-(1-methylethyl)phenyl]-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]- Preparation Products And Raw materials |
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