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| | marinobufagenin Basic information |
| Product Name: | marinobufagenin | | Synonyms: | marinobufagenin;14,15β-Epoxy-3β,5-dihydroxy-5β-bufa-20,22-dienolide;3β,5-Dihydroxy-14,15β-epoxy-5β-bufa-20,22-dienolide;3β,5β-Dihydroxy-14β,15β-epoxybufa-20,22-dienolide;Marinobufagin;Marinobufogenin;(3β,5β,15β)-3,5-Dihydroxy-14,15-epoxybufa-20,22-dienolide;Bufa-20,22-dienolide, 14,15-epoxy-3,5-dihydroxy-, (3β,5β,15β)- | | CAS: | 470-42-8 | | MF: | C24H32O5 | | MW: | 400.52 | | EINECS: | | | Product Categories: | Vasoconstrictor Agents;Enzyme Inhibitors | | Mol File: | 470-42-8.mol |  |
| | marinobufagenin Chemical Properties |
| Melting point | 224-225 °C | | Boiling point | 589.0±50.0 °C(Predicted) | | density | 1.31±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 3 mg/ml; DMF:PBS (pH 7.2) (1:8): 0.1 mg/ml; Ethanol: 1 mg/ml | | form | A crystalline solid | | pka | 14.77±0.70(Predicted) |
| | marinobufagenin Usage And Synthesis |
| Uses | Marinobufagin is a bufadienolide with anti-gastric cancer effect. A bioactive steroid that also functions as an endogenous Na/K-ATPase bufadienolide inhibitor that plays a major role in human cardiovascular diseases. | | Definition | ChEBI: Marinobufagenin is a cardiotonic steroid secreted by the toad Bufo rubescens and other related species such as Bufo marinus. An endogenous Na/K-ATPase inhibitor, it is a vasoconstrictor with effects similar to digitalis. It has a role as an EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor and an epitope. It is a steroid hormone and an epoxy steroid. It is functionally related to a (5beta)-bufadienolide. |
| | marinobufagenin Preparation Products And Raw materials |
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