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| Isotubulosine Basic information |
Product Name: | Isotubulosine | Synonyms: | (1'S)-10,11-Dimethoxytubulosan-8'-ol;1'-Isotubulosine;Isotubulosine;1H-Pyrido[3,4-b]indol-6-ol, 1-[[(2S,3R,11bS)-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-2,3,4,9-tetrahydro-, (1S)- | CAS: | 5610-39-9 | MF: | C29H37N3O3 | MW: | 475.62 | EINECS: | | Product Categories: | | Mol File: | 5610-39-9.mol | |
| Isotubulosine Chemical Properties |
| Isotubulosine Usage And Synthesis |
Description | A complex alkaloid occurring in Alangium lamarckii Thw., the base yields
colourless crystals from EtOH and is laevorotatory with [α]25D - 84° (c 1.0,
pyridine). The ultraviolet spectrum has been fully determined. In MeOH it shows
a single broad absorption maximum at 279 mJl. In 0.1 N/HC1 there is a very
small hypsochromic shift to 277 mJl while in 0.1 N/NaOH, there are two absorp_x0002_tion maxima at 279 and 319 mμ. Two methoxyl groups, two imino groups and
one hydroxyl group are present. The latter furnishes the O-methy1 ether, m.p.
163°C;[α]20D - 18.8° (MeOH). The above structure has been confirmed by
synthesis. | References | Popelak, Haack, Springler., Tetrahedron Lett., 5077 (1966) Synthesis: Openshaw, Whittaker., Chem. Commun., 131 (1966) |
| Isotubulosine Preparation Products And Raw materials |
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