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ChemStrong Scientific Co.,Ltd
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| Products Intro: |
Product Name:Teicoplanin A2-5
CAS:91032-38-1
Purity:95% HPLC Package:10mg;25mg;50mg;100mg
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| Company Name: |
BOC Sciences
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16314854226 |
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| Products Intro: |
Product Name:Teichomycin A2-5
CAS:91032-38-1
Purity:>98% by HPLC
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Lynnchem
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86-(0)29-85992781 17792393971 |
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Product Name:Teicoplanin A2-5
CAS:91032-38-1
Purity:>98% by HPLC Package:1mg;5mg
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| Company Name: |
Novachemistry
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44-20819178-90 02081917890 |
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| Products Intro: |
Product Name:Teicoplanin A2-5
CAS:91032-38-1
Purity:>98% by HPLC Package:1mg;5mg
|
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| | Teicoplanin A2-5 Basic information |
| Product Name: | Teicoplanin A2-5 | | Synonyms: | Ristomycin A aglycone, 34-O-2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyl-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-2-deoxy-2-(9-methyl-1-oxodecyl)amino-.beta.-D-glucopyranosyl-42-O-.alpha.-D-mannopyranosyl-;teicoplanin A2-5;Ristomycin A aglycone, 34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(9-methyl-1-oxodecyl)amino]-β-D-glucopyranosyl]-42-O-α-D-mannopyranosyl-;Teichomycin A2-5;Teicoplanin A2-5
DISCONTINUED. Please see T015500;34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(9-methyl-1-oxodecyl)amino]-β-D-glucopyranosyl]-42-O-α-D-mannopyranosyl-ristomycinAaglycone | | CAS: | 91032-38-1 | | MF: | C89H99Cl2N9O33 | | MW: | 1893.68 | | EINECS: | | | Product Categories: | | | Mol File: | 91032-38-1.mol |  |
| | Teicoplanin A2-5 Chemical Properties |
| density | 1.67±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in ethanol;Soluble in methanol;Soluble in DMSO;Soluble in dimethyl formamide | | form | lyophilisate | | pka | 2.88±0.40(Predicted) |
| | Teicoplanin A2-5 Usage And Synthesis |
| Uses | Teicoplanin A2-5 is an antibiotic against Gram positive bacteria. | | Uses | Teicoplanin A2-5 is the most non-polar analogue of a family of lipoglycopeptides produced by Actinoplanes teichomyceticus. Teicoplanins possess potent broad spectrum antibiotic activity against Gram positive bacteria, including MRSA and E. faecalis. | | Definition | ChEBI: A teicoplanin A2 that has 9-methyldecanoyl as the variable N-acyl group. | | Biological Activity | teicoplanin a2-5, derived from actinoplanes teichomyceticus, is a glycopeptide antibiotic which produces a broad spectrum of antibiotic activity against gram-positive bacteria.teicoplanin a2-5 is the most non-polar metabolite in the family of teicoplanins. teicoplanin, previously referred to in the literature as teichomycin, is a mixture of five closely related components of similar polarity, designated t-a2-1, 2, 3, 4 and 5 and of one more polar component, designated t-a3. additionally, as a glycopeptide antibiotic belonging to the same family as vancomycin, teicoplanin blocks cell wall synthesis in bacillus subtilis, which is accompanied by an intracellular accumulation of udp-n-acetylmuramyl-pentapetide [1]. due to the greater antibacterial activity of teicoplanin than other agents, it has been thoroughly studied as a β-1actamase-resistant agent for the treatment of human infections caused by streptococci and staphylococci, including enterococci [2]. | | references | [1]. somma, s., gastaldo, l., & corti, a. teicoplanin, a new antibiotic from actinoplanes teichomyceticus nov. sp. antimicrobial agents and chemotherapy. 1984; 26(6): 917-923.
[2]. traina, g., & bonati, m. pharmacokinetics of teicoplanin in man after intravenous administration. journal of pharmacokinetics and biopharmaceutics. 1984;12(2): 119-128. |
| | Teicoplanin A2-5 Preparation Products And Raw materials |
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