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| | Galloflavin Basic information |
| Product Name: | Galloflavin | | Synonyms: | Galloflavin;3,8,9,10-Tetrahydroxy-pyrano[3,2-c][2]benzopyran-2,6-dione;NSC 107022;6,8,9,10-tetrahydroxypyrano[3,2-c]isochromene-2,3-dione;3,8,9,10-Tetrahydroxy-pyrano[3,2-c][2]benzopyran-2,6-dione,NSC 107022;Pyrano[3,2-c][2]benzopyran-2,6-dione, 3,8,9,10-tetrahydroxy-;3,8,9,10-Tetrahydroxypyrano[3,2-C]Isochromene-2,6-Dione;Galloflavin（NSC-107022） | | CAS: | 568-80-9 | | MF: | C12H6O8 | | MW: | 278.17 | | EINECS: | | | Product Categories: | Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals | | Mol File: | 568-80-9.mol |  |
| | Galloflavin Chemical Properties |
| Melting point | >140°C (dec.) | | Boiling point | 727.6±60.0 °C(Predicted) | | density | 2.10±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | DMSO: soluble5mg/mL, clear | | form | powder | | pka | 6.75±0.20(Predicted) | | color | light yellow to light brown |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | 3 |
| | Galloflavin Usage And Synthesis |
| Uses | Galloflavin is a novel inhibitor of lactate dehydrogenase and is a potential anticancer agent. This compound is suitable for lactate dehydrogenase (LDH) related research. | | Biochem/physiol Actions | Galloflavin is an inhibitor of lactate dehydrogenase (LDH). The compound blocks both isoforms of (LDH-A and –B) with Ki values of 5.5 and 15 μM, respectively. Inhibition of the glycolytic pathway by galloflavin induces oxidative stress and apoptosis in breast tumor cell lines. |
| | Galloflavin Preparation Products And Raw materials |
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