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Sigma-Aldrich
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021-61415566 800-8193336 |
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Product Name:IDT307 CAS:1141-41-9 Purity:>=98% (HPLC) Package:5MG Remarks:SML0756-5MG
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Product Name: | APP+ | Synonyms: | 4-(4-Dimethylamino)phenyl-1-methylpyridinium iodide;4-[p-(Dimethylamino)phenyl]-1-methylpyridinium iodide;IDT307;IDT307 >=98% (HPLC);4-[4-(Dimethylamino)phenyl]-N-methylpyridinium iodide | CAS: | 1141-41-9 | MF: | C14H17IN2 | MW: | 340.20265 | EINECS: | | Product Categories: | | Mol File: | 1141-41-9.mol | |
Melting point | 180-182 °C | storage temp. | -20°C | solubility | DMSO: soluble15mg/mL, clear | form | powder | color | orange to dark orange-red |
Hazard Codes | T | Risk Statements | 25 | Safety Statements | 45 | RIDADR | UN 2811 6.1 / PGIII | WGK Germany | 3 |
Biochem/physiol Actions | IDT307 (APP+) is a fluorescent analogue of the dopaminergic neurotoxin MPP+ monoamine transporter substrate that fluoresces after uptake into cells. IDT307 is a substrate for the dopamine transporter (DAT), norepinephrine transporter (NET), and serotonin transporter (SERT). IDT307 (APP+) was found to label catecholamine neuronal cell bodies with high selectivity in midbrain and was used to investigate SERT function in lymphocytes and platelets. |
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