ChemicalBook CAS DataBase List 2-Methyl-1,3-cyclopentanedione

2-Methyl-1,3-cyclopentanedione synthesis

8synthesis methods

Product Name:2-Methyl-1,3-cyclopentanedione
CAS Number:765-69-5
Molecular formula:C6H8O2
Molecular Weight:112.13

614-45-9 Synthesis

614-45-9
225 suppliers
$19.30/5g

3859-41-4 Synthesis

3859-41-4
290 suppliers
$6.00/1g

765-69-5
251 suppliers
$6.00/5g

Yield:765-69-5 68%

Reaction Conditions:

with acetic acid;copper(l) chloride at 120;

Steps:

24 Example 24: Preparation of 2-methyl-1,3-cyclopentanedione
In order to 1,3-cyclopentanedione, tert-butyl peroxybenzoate is used as a raw material, the reaction steps are as follows:In the reaction flask by adding 1,3-cyclopentanedione (0.098g, 1mmol), tert-butyl peroxybenzoate (0.58g, 3mmol), CuCl (0.01g, 0 . 1mmol) and 2 ml acetic acid, 120 °C reaction;TLC until the complete end tracking of the reaction;After the reaction the crude product by column chromatography (petroleum ether: ethyl acetate = 40:1), to obtain the target product (yield 68%).

References:

Soochow University;Zou, Jianping;Zhou, Shaofang;Zhang, Peizhi;Zhang, Guoyu;Zhou, Pengjun;Li, Chengkun CN105254483, 2016, A Location in patent:Paragraph 0044

FullText

110-15-6 Synthesis