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2-Butenoic acid, 4-(3-hydroxy-2-nitrophenyl)-4-oxo- synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 25 percent / Cu(NO3)2*2.5H2O / acetic acid; acetic anhydride / 10 - 15 °C
2: 55 percent / 24 h / 120 °C

References:

Mizdrak, Jasminka;Hains, Peter G.;Kalinowski, Danuta;Truscott, Roger J.W.;Davies, Michael J.;Jamie, Joanne F. [Tetrahedron,2007,vol. 63,# 23,p. 4990 - 4999]