ChemicalBook CAS DataBase List METHYL 2-CHLORONICOTINATE

METHYL 2-CHLORONICOTINATE synthesis

11synthesis methods

Product Name:METHYL 2-CHLORONICOTINATE
CAS Number:40134-18-7
Molecular formula:C7H6ClNO2
Molecular Weight:171.58

67-56-1 Synthesis

67-56-1
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$7.29/5ml-f

2942-59-8 Synthesis

2942-59-8
780 suppliers
$5.00/25g

40134-18-7
224 suppliers
$6.00/5g

Yield:40134-18-7 93%

Reaction Conditions:

with thionyl chloride for 8 h;Reflux;

Steps:

1.1 preparation of compound II
To the 250 ml flask is added in three 15.76g (0.1 µM) 2 - chloro -3 - picolinic acid, 100 ml methanol, under the ice-bath adds by drops 17.85g (0.15 µM) thionyl chloride, stirring and heating to reflux, the stirring reaction 8h. Thin layer chromatography tracking response, the raw materials point disappears, stopping the reaction. Reduced pressure distillation to remove the solvent to obtain light yellow 15.95g, yield 93%

References:

Qingdao University of Science and Technology;Wang Minghui;Yuan Jianpo;Huang Xuesong;Xu Liangzhong CN105061399, 2017, B Location in patent:Paragraph 0010; 0029; 0030

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2942-59-8 Synthesis

2942-59-8
780 suppliers
$5.00/25g

40134-18-7
224 suppliers
$6.00/5g

References

2942-59-8 Synthesis

2942-59-8
780 suppliers
$5.00/25g