Thiamethoxam synthesis
- Product Name:Thiamethoxam
- CAS Number:153719-23-4
- Molecular formula:C8H10ClN5O3S
- Molecular Weight:291.71
105827-91-6
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Yield:153719-23-4 98%
Reaction Conditions:
with potassium carbonate in N,N-dimethyl-formamide at 50; for 16 h;
Steps:
3
In a 500 ml round bottom flask, 70 g of solvent N, N-dimethylformamide was added successively,150 g of anhydrous potassium carbonate,80g3-methyl-4-nitroimino-1,3,5-oxadiazine,Stir to raise the temperature to 50 ,110 g of 2-chloro-5-chloromethylthiazole was added at a rate of 50 ml / h in a 250 ml constant pressure dropping funnel,Control the temperature does not exceed 50 ,2-Chloro-5-chloromethylthiazole was slowly added dropwise,After dripping,Control the temperature at 50 incubation reaction 16h,After the insulation,Cooling to 10 ,filter,Thiamethoxam drying to obtain a solid.In this example, thiamethoxam was analyzed by liquid chromatography to give a content of 98.4%The yield of thiamethoxazole was 98%The recoveries of N, N-dimethylformamide were 92%.
References:
CN106188032,2016,A Location in patent:Paragraph 0017-0019
153719-38-1
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105827-91-6
374 suppliers
$6.00/5g
153719-23-4
337 suppliers
$39.00/50mg
![Guanidine, N-[(2-chloro-5-thiazolyl)methyl]-N'-nitro-](/CAS/20180527/GIF/135018-15-4.gif)
135018-15-4
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153719-23-4
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