ChemicalBook--->CAS DataBase List--->100999-26-6

100999-26-6

100999-26-6 Structure

100999-26-6 Structure
IdentificationBack Directory
[Name]

CY 208-243
[CAS]

100999-26-6
[Synonyms]

CY 208-243
(6aR)-4,6,6aα,7,8,12bβ-Hexahydro-7-methylindolo[4,3-ab]phenanthridine
(6aR,12bβ)-4,6,6a,7,8,12b-Hexahydro-7-methylindolo[4,3-ab]phenanthridine
(6aα,12bβ)-4,6,6a,7,8,12b-Hexahydro-7-methylindolo[4,3-ab]phenanthridine
(-)-(6AR,12BR)-4,6,6A,7,8,12B-HEXAHYDRO-7-METHYLINDOLO[4,3-A]PHENANTHRIDIN
(-)-(6aR,12bR)-4,6,6a,7,8,12β-Hexahydro-7-methylindolo[4,3-a]phenanthridin
[6aR,12bR,(-)]-4,6,6a,7,8,12b-Hexahydro-7-methylindolo[4,3-ab]phenanthridine
Indolo[4,3-ab]phenanthridine, 4,6,6a,7,8,12b-hexahydro-7-methyl-, (6aR,12bR)-
[Molecular Formula]

C19H18N2
[MDL Number]

MFCD06407823
[MOL File]

100999-26-6.mol
[Molecular Weight]

274.36
Chemical PropertiesBack Directory
[Boiling point ]

466.5±33.0 °C(Predicted)
[density ]

1.225±0.06 g/cm3(Predicted)
[storage temp. ]

Store at RT
[solubility ]

Soluble to 100 mM in DMSO
[form ]

Powder
[pka]

17.40±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

CY 208-243 is a selective D1DR receptor agonist.
[Definition]

ChEBI:LSM-3788 is a member of phenanthridines.
[Biological Activity]

Centrally active dopamine D 1 receptor agonist, selective over D 2 receptor sites. Stimulates adenylate cyclase in rat striatal homogenates with an EC 50 of 125 nM. Unlike SKF 38393 ((?-1-Phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol hydrobromide ), it exerts anti-Parkinsonian activity in animal models.
[storage]

Store at RT
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