ChemicalBook--->CAS DataBase List--->10285-06-0

10285-06-0

10285-06-0 Structure

10285-06-0 Structure
IdentificationBack Directory
[Name]

INTERMEDINE
[CAS]

10285-06-0
[Synonyms]

C10330
INTERMIDINE
(+)-Intermedine
9-(+)-Trachelanthylretronecine
(1R)-2,3,5,7aβ-Tetrahydro-7-[[(2S,3R)-2-isopropyl-2,3-dihydroxybutyryl]oxymethyl]-1H-pyrrolizine-1-ol
(2S,3R)-2,3-Dihydroxy-2-isopropylbutanoic acid [[(5R,6R)-6-hydroxy-1-azabicyclo[3.3.0]oct-3-en-4-yl]methyl] ester
Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, [(1R,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl]methyl ester, (2S,3R)-
[Molecular Formula]

C15H25NO5
[MOL File]

10285-06-0.mol
[Molecular Weight]

299.36
Chemical PropertiesBack Directory
[Melting point ]

140-141 °C
[Boiling point ]

463.3±45.0 °C(Predicted)
[density ]

1.26±0.1 g/cm3(Predicted)
[pka]

12.59±0.29(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P264-P270-P301+P312-P330-P501
[RIDADR ]

1544
[HazardClass ]

6.1(b)
[PackingGroup ]

III
Hazard InformationBack Directory
[Uses]

Intermedine-D7 is a labelled analogue of Intermedine (I666660). Intermedine is an unsaturated monoester pyrrolizidine alkaloid that is extracted from the seeds of Amsinckia intermedia, a tarweed that causes enzootic hepatic cirrhosis in horses and hard liver disease in cattle. Intermedine is also a diastereomer of Lycopsamine (L487525), a pyrrolizidine alkaloid that is found in honey and in comfrey (a topical anti-inflammatory agent used to treat patients with arthritis and gout).
[Definition]

ChEBI: A carboxylic ester compound formed from condensation between retronecine and (2S,3R)-2,3-dihydroxy-2-isopropylbutanoic acid.
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