| Identification | Back Directory | [Name]
Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate | [CAS]
112889-02-8 | [Synonyms]
diethyl n-[5-methylamino-2-thenoyl]-l-glutamate
Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate USP/EP/BP
(S)-Diethyl 2-(5-(MethylaMino)thiophene-2-carboxaMido)pentanedioate
n-[[5-(methylamino)-2-thienyl]carbonyl]-l-glutamic acid diethyl ester
iethyl(2S)-2-[[5-(methylamino)thiophene-2-carbonyl]amino]pentanedioate
L-Glutamic acid, N-[[5-(methylamino)-2-thienyl]carbonyl]-, 1,5-diethyl ester | [Molecular Formula]
C15H22N2O5S | [MDL Number]
MFCD09750956 | [MOL File]
112889-02-8.mol | [Molecular Weight]
342.41 |
| Chemical Properties | Back Directory | [Boiling point ]
519.6±50.0 °C(Predicted) | [density ]
1.231 | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [pka]
12.89±0.46(Predicted) |
| Hazard Information | Back Directory | [Uses]
N-[[5-(Methylamino)-2-thienyl]carbonyl]-L-glutamic Acid Diethyl Ester can be used as reactant/reagent for synthetic preparation of Raltitrexed (anticancer agent). An intermediate or impurity in the synthesis of Raltitrexed (R100500). Raltitrexed (R100500) is folate-based inhibitor of thymidylate synthase; rapidly and extensively metabolized to its more potent polyglutamate derivatives. Antineoplastic. |
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| Company Name: |
SynAsst Chemical.
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| Tel: |
021-60343070 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15848/0.htm |
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