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1189-94-2

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1189-94-2 Structure

1189-94-2 Structure
IdentificationBack Directory
[Name]

MEVALONIC ACID-5-PHOSPHATE
[CAS]

1189-94-2
[Synonyms]

phosphomevalonic acid
MEVALONIC ACID-5-PHOSPHATE
Mevalonic Acid 5-Phosphate Hydrate
[Molecular Formula]

C6H13O7P
[MDL Number]

MFCD00189915
[MOL File]

1189-94-2.mol
[Molecular Weight]

228.14
Hazard InformationBack Directory
[Uses]

Mevalonic Acid 5-Phosphate is used in the a key step in the mevalonate pathway for isoprenoid and sterol biosynthesis.
[Definition]

ChEBI: 3-hydroxy-3-methyl-5-phosphonooxypentanoic acid is a monoalkyl phosphate.
[Purification Methods]

Purify the acid by conversion to the tricyclohexylammonium salt (m 154-156o) by treatment with cyclohexylamine. Crystallise it from water/acetone at -15o. Alternatively, the phosphate is chromatographed through an ion-exchange resin or paper (Whatman No 1) in a system of isobutyric acid/ammonia/water (66:3:30; RF 0.42). Store it as the cyclohexylammonium salt.
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