| Identification | Back Directory | [Name]
YM17E | [CAS]
124900-72-7 | [Synonyms]
YM17E
Urea, N,N''-[1,3-phenylenebis(methylene)]bis[N-cycloheptyl-N'-[4-(dimethylamino)phenyl]- (9CI) | [Molecular Formula]
C40H56N6O2 | [MOL File]
124900-72-7.mol | [Molecular Weight]
652.91 |
| Chemical Properties | Back Directory | [Boiling point ]
862.7±65.0 °C(Predicted) | [density ]
1.16±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
14.03±0.70(Predicted) |
| Hazard Information | Back Directory | [Biological Activity]
YM17E is an inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT) with IC50 of 44 nM in vitro in rabbit liver microsomes. | [in vitro]
YM17E is as potent in inhibiting ACAT activity in the liver as in the intestine, with IC 50 values of 45 and 34 nM, respectively. | [target]
IC50: 44 nM (ACAT in rabbit liver microsomes) | [storage]
Store at -20°C |
|
| Company Name: |
cjbscvictory
|
| Tel: |
13348960310 13348960310 |
| Website: |
http://www.weikeqi-biotech.com/ |
| Company Name: |
MedChemExpress
|
| Tel: |
021-58955995 |
| Website: |
www.medchemexpress.com |
|