| Identification | Back Directory | [Name]
Eltanolone | [CAS]
128-20-1 | [Synonyms]
SKF 6455
Kabi2213
Kabi-2213
Kabi 2213
NSC 82867
ELTANOLONE
PREGNANOLONE
EPIPREGNANOLONE
Pregnanolone II
3α,5β-Pregnanolone
Pregnan-3α-ol-20-one
PREGNAN-3A-OL-20-ONE
pregnan-3a-ol-20-one
5-Pregnan-3-ol-20-one
5B-PREGNAN-3A-OL-20-ONE
5B-Pregnan-3α-ol-20-one
5A-PREGNAN-3A-OL-20-ONE
Pregnanolone (Solution)
5β-Pregnan-3α-ol-20-one
5A-PREGNAN-3SS-OL-20-ONE
Pregnan-3alpha-ol-20-one
5-β-Pregnan-3a-ol-20-one
3alpha,5beta-Pregnanolone
5beta-Pregnan-3a-ol-20-one
3a,5b-epimeric pregnanolone
3a,5b-Tetrahydroprogesterone
3a,5b-Epimeric pregnanolone
3A-HYDROXY-5B-PREGNAN-20-ONE
3α-Hydroxy-20-oxo-5β-pregnane
5BETA-PREGNAN-3ALPHA-OL-20-ONE
(3α,5β)-3-Hydroxy-pregnan-20-one
3alpha,5beta-Epimeric pregnanolone
3ALPHA-HYDROXY-5BETA-PREGNAN-20-ONE
3α-Hydroxy-5β-tetrahydroprogesterone
3-alpha-hydroxy-5-beta-pregnan-20-on
Pregnan-20-one, 3-hydroxy-, (3a,5b)-
3a-Hydroxy-5b-tetrahydroprogesterone
5beta-Pregnan-20-one, 3alpha-hydroxy-
3-Deoxo-3α-hydroxy-5β-dihydroprogesterone
Pregnan-20-one, 3-hydroxy-, (3alpha,5beta)-
3ALPHA-HYDROXY-5BETA-TETRAHYDRO-PROGESTERONE
5A-PREGNAN-3B-OL-20-ONE ENTERPRISE STANDARD,98+%
3α-Hydroxy-5β-pregnan-20-one, 3α-Hydroxy-5β-tetrahydroprogesterone, Pregnanolone
1-[(3R,5R,8R,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone | [Molecular Formula]
C21H34O2 | [MDL Number]
MFCD00067137 | [MOL File]
128-20-1.mol | [Molecular Weight]
318.49 |
| Chemical Properties | Back Directory | [Melting point ]
149°C | [alpha ]
D23 +59.6° (c = 0.3 in chloroform); D26 +108.5 ±1° (c = 9.23 mg/1.23 ml abs ethanol) | [Boiling point ]
397.64°C (rough estimate) | [density ]
1.0234 (rough estimate) | [refractive index ]
1.5344 (estimate) | [storage temp. ]
Store at RT | [solubility ]
Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
15.12±0.70(Predicted) | [color ]
White to Off-White | [Water Solubility ]
8mg/L(room temperature) | [NIST Chemistry Reference]
3Alpha-hydroxy-5beta-pregnan-20-one(128-20-1) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
40 | [Safety Statements ]
22-36 | [WGK Germany ]
3 | [RTECS ]
TU4384000 | [Toxicity]
LD50 in mice, rats (mg/kg): 66 ± 10, 27.5 ± 2.4 i.v. (Gyermek) |
| Hazard Information | Back Directory | [Uses]
A hyponotic-anaesthetic agent | [Uses]
A hyponotic-anaesthetic agent. | [Definition]
ChEBI: The 3alpha-stereoisomer of 3-hydroxy-5beta-pregnan-20-one. | [Biological Activity]
GABA A receptor positive allosteric modulator. Neuroactive steroid. | [Biochem/physiol Actions]
5β-Pregnan-3α-ol-20-one or pregnanolone is a neurosteroid that acts as a positive allosteric modulator (PAMs) of γ-aminobutyric acid A receptors (GABAARs). It mediates anti-convulsive, anxiolytic and sedative effects. Pregnanolone inhibits γ-aminobutyric acid C receptor (GABAC) receptor-based response and favors GABAA?receptor-mediated currents. | [storage]
Store at RT |
|
| Company Name: |
BOC Sciences
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1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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