| Identification | Back Directory | [Name]
NVP-BKM120 (Hydrochloride) | [CAS]
1312445-63-8 | [Synonyms]
CS-2154
BKM 120AAA
Buparlisib HCl
NVP-BKM120 HCl
BKM-120 (HCl salt)
NVP-BKM120 HCl salt
BKM120 hydrochloride
BKM-120 hydrochloride
BKM 120 hydrochloride
NVP-BKM120 (HYDROCHLORI
Buparlisib hydrochloride
NVP-BKM120 (Hydrochloride)
BKM-120 HYDROCHLORIDE;BUPARLISIB HYDROCHLORIDE
BKM-120 HYDROCHLORIDE; BKM120 HYDROCHLORIDE; BKM 120 HYDROCHLORIDE
5-(2,6-DiMorpholinopyriMidin-4-yl)-4-(trifluoroMethyl)pyridin-2-aMine hydrochloride
5-(2,6-Di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine hydrochloride (1:1) | [Molecular Formula]
C18H22ClF3N6O2 | [MDL Number]
MFCD22124511 | [MOL File]
1312445-63-8.mol | [Molecular Weight]
446.854 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
≥44.7 mg/mL in DMSO; ≥52.8 mg/mL in H2O with gentle warming; ≥96 mg/mL in EtOH with gentle warming | [form ]
solid | [InChI]
InChI=1S/C18H21F3N6O2.ClH/c19-18(20,21)13-9-15(22)23-11-12(13)14-10-16(26-1-5-28-6-2-26)25-17(24-14)27-3-7-29-8-4-27;/h9-11H,1-8H2,(H2,22,23);1H | [InChIKey]
DGPLYAXBXJXEID-UHFFFAOYSA-N | [SMILES]
C(C1=CC(N)=NC=C1C1=NC(N2CCOCC2)=NC(N2CCOCC2)=C1)(F)(F)F.Cl |
| Hazard Information | Back Directory | [Uses]
NVP-BKM 120-d16 Hydrochloride is the salt, labeled analogue of NVP-BKM 120 (N925760), a novel anti-tumor active compound that is selective in that it inhibits specifically PI3 kinase activating cell death in glioma cells. Glioma cells being those that proliferate from tumors in the brain or the spine. |
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| Company Name: |
NCE Biomedical Co.,Ltd.
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| Tel: |
4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15748/0.htm |
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