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132682-98-5

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132682-98-5 Structure

132682-98-5 Structure
IdentificationBack Directory
[Name]

Glufosfamide
[CAS]

132682-98-5
[Synonyms]

D 19575
Glufosfamide
Glufosfamide (D-19575
β-D-Glucopyranose, 1-[N,N'-bis(2-chloroethyl)phosphorodiamidate]
GLUFOSFAMIDE,B-D-GLUCOPYRANOSE, 1-(N,N'-BIS(2-CHLOROETHYL)PHOSPHORODIAMIDATE)-
(2S,3R,4S,5S,6R)-2-Bis(2-chloroethylamino)phosphoryloxy-6-(hydroxymethyl)oxane-3,4,5-triol
[Molecular Formula]

C10H21Cl2N2O7P
[MDL Number]

MFCD00914610
[MOL File]

132682-98-5.mol
[Molecular Weight]

383.16
Chemical PropertiesBack Directory
[Boiling point ]

569.9±60.0 °C(Predicted)
[density ]

1.56±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[pka]

12.58±0.70(Predicted)
Safety DataBack Directory
[Hazardous Substances Data]

132682-98-5(Hazardous Substances Data)
[Toxicity]

LD50 in rats, mice (mg/kg): 1575, 1575 i.v.; 1470, 1470 orally (Pohl)
Hazard InformationBack Directory
[Uses]

Glufosfamide is an alkylating cytotoxic agent with increased antitumor selectivity and active transmembrane transport mechanism, that belongs to the oxazaphosphorine class. It is an attractive new agent for cancer therapy in humans.
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