| Identification | Back Directory | [Name]
10'-desmethoxystreptonigrin | [CAS]
136803-89-9 | [Synonyms]
-Desmethoxystreptonigrin
10'-desmethoxystreptonigrin
DesMethoxystreptonigrin, 10'-
2-Pyridinecarboxylic acid, 5-amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolinyl)-4-(2-hydroxy-3-methoxyphenyl)-3-methyl- | [Molecular Formula]
C24H20N4O7 | [MDL Number]
MFCD01692195 | [MOL File]
136803-89-9.mol | [Molecular Weight]
476.443 |
| Hazard Information | Back Directory | [Uses]
10’-Desmethoxystreptonigrin is a potent inhibitor of farnesylation of RAS P21 protein. | [Uses]
10'-Desmethoxystreptonigrin is a close analogue of streptonigrin produced by selected Streptomyces species. It is a moderately potent inhibitor of farnesylation of RAS P21 protein, 3-fold more active than streptonigrin. 10'-Desmethoxystreptonigrin has also been reported to have potent and broad spectrum antibacterial and antitumor activity. | [Uses]
10'-Desmethoxystreptonigrin is a close analogue of streptonigrin, produced by selected Streptomyces species. It is a moderately potent inhibitor of farnesylation of RAS P21 protein, 3-fold more active than streptonigrin. 10'-Desmethoxystreptonigrin has also been reported to have potent and broad spectrum antibacterial and antitumour activity. | [storage]
Store at -20°C |
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