| Identification | Back Directory | [Name]
(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide | [CAS]
1417997-93-3 | [Synonyms]
CS-2693
MDK-7933
HDAC8-IN-1
HDAC8-IN-22d
HDAC8 inhibitor 1
HDAC8-IN-1 ,MDK7933
HDAC8 inhibitor 22d
(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide
(2E)-N-Hydroxy-3-(5-methoxy[1,1':4',1''-terphenyl]-2-yl)-2-propenamide
2-Propenamide, N-hydroxy-3-(5-methoxy[1,1':4',1''-terphenyl]-2-yl)-, (2E)- | [Molecular Formula]
C22H19NO3 | [MDL Number]
MFCD31619280 | [MOL File]
1417997-93-3.mol | [Molecular Weight]
345.39 |
| Hazard Information | Back Directory | [Description]
HDAC8-IN-1 is an inhibitor of histone deacetylase 8 (HDAC8; IC50 = 27.2 nM). It is selective for HDAC8 over HDAC1-3, -4, -6, -10, and -11 (IC50s = ≥3,000 nM for all). HDAC8-IN-1 is cytotoxic to A549, H1299, and CL1-5 lung cancer cells (IC50s = 7.9, 7.2, and 7 μM, respectively). | [Uses]
(2E)-N-Hydroxy-3-(5-methoxy[1,1'':4'',1''''-terphenyl]-2-yl)-2-propenamide, is a HDAC8 inhibitor with an IC50 of 27.2 nM. | [storage]
Store at -20°C |
|
| Company Name: |
Twochem Co.Ltd
|
| Tel: |
021-58111628 15800915896 |
| Website: |
http://www.twochem.com |
|