ChemicalBook--->CAS DataBase List--->145195-63-7

145195-63-7

145195-63-7 Structure

145195-63-7 Structure
IdentificationBack Directory
[Name]

CIS-ENTACAPONE
[CAS]

145195-63-7
[Synonyms]

(Z)-Entacapone
CIS-ENTACAPONE
Entacapen impurity A
Entacapone-d10 (cis)
Entacapone impurity A
Entacapone impurity A -I
Entacapone EP IMpurity A
Entacapone impurity A CRS
Entacapone Related CoMpound A
Z Entacapone/ EP impurity A/RC A
Entacapone USP Related Compound A
(2Z)-2-Cyano-3-(3,4-dihydroxy-5-nit
Entacapone EP Impurity A (cis-Entacapone)
Entacapone Impurity 1(Entacapone EP Impurity A)
Entacapone Impurity 17(Entacapone EP Impurity A)
(Z)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylacrylamide
(Z)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide
(2Z)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide
(2Z)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide
2-Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-, (2Z)-
Entacapone Related Compound A (25 mg) ((Z)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylacrylamide)
Entacapone Related Compound A ((Z)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylacrylamide) (1235944)
[Molecular Formula]

C14H15N3O5
[MDL Number]

MFCD00869878
[MOL File]

145195-63-7.mol
[Molecular Weight]

305.29
Chemical PropertiesBack Directory
[Melting point ]

142-144°C
[storage temp. ]

Hygroscopic, -20°C Freezer, Under Inert Atmosphere
[solubility ]

Dichloromethane (Slightly), Methanol (Slightly)
[form ]

neat
[color ]

Yellow to Orange
Safety DataBack Directory
[HS Code ]

2926900005
Hazard InformationBack Directory
[Description]

cis-Entacapone is a metabolite of the catechol-O-methyltransferase (COMT) inhibitor entacapone . It is also a potential impurity found in commercial preparations of entacapone and a degradant of entacapone formed by UV light exposure.
[Chemical Properties]

Orange Solid
[Uses]

(Z)-Isomer of Entacapone polymorphic form B. Antiparkinsonian
[Uses]

cis-Entacapone (Entacapone EP Impurity A) is the (Z)-Isomer of Entacapone polymorphic form B. Antiparkinsonian.
[Definition]

ChEBI: 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide is a hydroxycinnamic acid.
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