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1542166-82-4

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1542166-82-4 Structure

1542166-82-4 Structure
IdentificationBack Directory
[Name]

15-deoxy-Δ12,14-Prostaglandin J2-d4
[CAS]

1542166-82-4
[Synonyms]

VHRUMKCAEVRUBK-NSTSLKHFSA-N
15-deoxy-Δ12,14-Prostaglandin J2-d4
[Molecular Formula]

C20H28O3
[MDL Number]

MFCD00797665
[MOL File]

1542166-82-4.mol
[Molecular Weight]

316.44
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: >100 mg/ml (from PGD2),DMSO: >50 mg/ml (from PGD2),Ethanol: >75 mg/ml (from PGD2)
Safety DataBack Directory
[Symbol(GHS) ]


GHS02,GHS07
[Signal word ]

Danger
Hazard InformationBack Directory
[Description]

15-deoxy-Δ12,14-PGJ2-d4 contains four deuterium atoms at the 3, 3'', 4, and 4'' positions. It is intended for use as an internal standard for the quantification of 15-deoxy-Δ12,14-PGJ2 by GC- or LC-mass spectrometry. 15-deoxy-Δ12,14-Prostaglandin J2 (15-deoxy-Δ12,14-PGJ2) is a metabolite of PGJ2. 15-deoxy-Δ12,14-PGJ2 is formed from PGD2 by the elimination of two molecules of water. It binds selectively to PPARγ with an EC50 of 2 μM in a murine chimera system. 15-deoxy-Δ12,14-PGJ2 is more potent than PGD2, Δ12-PGJ2, and PGJ2 in stimulating lipogenesis in C3H10T1/2 cells. The EC50 for induction of adipocyte differentiation in cultured fibroblasts is 7 μM.
[storage]

Store at -20°C
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