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162401-62-9

162401-62-9 Structure

162401-62-9 Structure
IdentificationBack Directory
[Name]

3-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid
[CAS]

162401-62-9
[Synonyms]

RofluM
Roflumilast Impurity J
Roflumilast Acid Impurity
Roflumilast intermediate B
RofluMilast InterMediate II
Roflumilast Carboxylic Acid Impurity
CYCLOPROPYL DIFLUOROMETHOXYBENOZOIC ACID
3-CyclopropylMethoxy-4-isopropoxy-benzoic acid
3-CyclopropyMethoxy-4-difluoroMethoxy benzoic acid
3-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid
Benzoic acid, 3-(cyclopropylMethoxy)-4-(difluoroMethoxy)-
3-Cyclopropylmethoxy-4-difluoromethoxybenzoic acid, >=98%
Roflumilast intermediate (3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzoic acid)
[EINECS(EC#)]

605-288-7
[Molecular Formula]

C12H12F2O4
[MDL Number]

MFCD04621687
[MOL File]

162401-62-9.mol
[Molecular Weight]

258.219
Chemical PropertiesBack Directory
[Melting point ]

118-120℃
[Boiling point ]

356.4±37.0 °C(Predicted)
[density ]

1.355±0.06 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

3.87±0.10(Predicted)
[color ]

White to Off-White
[InChIKey]

IGFDIFLMMLWKKY-UHFFFAOYSA-N
[CAS DataBase Reference]

162401-62-9
Safety DataBack Directory
[Hazard Codes ]

T
[Risk Statements ]

25
[Safety Statements ]

45
[RIDADR ]

2811
[HazardClass ]

6.1
[PackingGroup ]

Hazard InformationBack Directory
[Uses]

An impurity and intermediate in the preparation of selective phosphodiesterase 4 (PDE4) inhibitor, Roflumilast (R639700).
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