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175735-93-0

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175735-93-0 Structure

175735-93-0 Structure
IdentificationBack Directory
[Name]

α-Conotoxin MII
[CAS]

175735-93-0
[Synonyms]

α-Conotoxin MII
[Molecular Formula]

C67H103N23O22S4
[MDL Number]

MFCD18427712
Chemical PropertiesBack Directory
[form ]

Powder
[Water Solubility ]

Soluble to 1 mg/ml in water
Safety DataBack Directory
[Symbol(GHS) ]


GHS06
[Signal word ]

Danger
[Hazard statements ]

H310-H300-H330
[Precautionary statements ]

P264-P270-P301+P310-P321-P330-P405-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P262-P264-P270-P280-P302+P350-P310-P322-P361-P363-P405-P501
Hazard InformationBack Directory
[Biological Activity]

α-Conotoxin MII (α-CTxMII) can be isolated from the sea snail Conus magus and potently inhibits the α3β2 subunit of the nAChR receptor with an IC50 value of 0.5 nM. α-Conotoxin MII (α-CTxMII) potently inhibits β3-containing neuronicotine receptors.
[in vitro]

α-Conotoxin MII (0.5-3.5 nM) blocks ACh responses in oocytes expressing α3β2 nicotinic acetylcholine receptors.

[target]

IC50: 0.5 nM (α3β2).

[storage]

Store at -20°C
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