| Identification | Back Directory | [Name]
2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanaminehydrochloride | [CAS]
177172-49-5 | [Synonyms]
R-568
R 568 hydrochloride
Tecalcet (Hydrochloride)
R-568 hydrochloride >=95% (HPLC)
2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanaminehydrochloride
(R)-3-(2-Chlorophenyl)-N-(1-(3-methoxyphenyl)ethyl)propan-1-amine hydrochloride
3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine, hydrochloride
Benzenepropanamine, 2-chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-, hydrochloride (1:1) | [Molecular Formula]
C18H23Cl2NO | [MDL Number]
MFCD16038895 | [MOL File]
177172-49-5.mol | [Molecular Weight]
340.287 |
| Hazard Information | Back Directory | [Description]
Calcium-sensing receptor (CaSR) is a G protein-coupled receptor that is involved in calcium homeostasis. Activation of CaSR on parathyroid cells decreases the secretion of parathyroid hormone (PTH), which in turn reduces blood calcium concentration. R-568 is a calcimimetic compound that can allosterically activate or positively modulate the human CaSR. It dose-dependently decreases circulating levels of PTH in both normal individuals and patients with primary hyperparathyroidism in clinical trials. R-568 is used in research to explore novel actions of CaSR. | [Uses]
Treatment of hyperparathyroidism and related disorders,
such as hypercalcemia (reduction of PTH secretion
through modulation of calcium ion receptors on parathyroid
cells). | [Brand name]
Norcalcin (Amgen). | [storage]
Store at -20°C |
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BOC Sciences
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https://www.bocsci.com |
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