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1971920-73-6

1971920-73-6 Structure

1971920-73-6 Structure
IdentificationBack Directory
[Name]

(R)-1-(1-acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one
[CAS]

1971920-73-6
[Synonyms]

PRN-2246
SAR442168
Tolebrutinib
(R)-1-(1-acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one
(R,E)-1-(1-acryloylpiperidin-3-yl)-4-amino-3-(4-(penta-2,4-dien-2-yloxy)phenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one
2H-Imidazo[4,5-c]pyridin-2-one, 4-amino-1,3-dihydro-1-[(3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]-3-(4-phenoxyphenyl)-
[Molecular Formula]

C26H25N5O3
[MDL Number]

MFCD32710277
[MOL File]

1971920-73-6.mol
[Molecular Weight]

455.51
Chemical PropertiesBack Directory
[Boiling point ]

698.1±65.0 °C(Predicted)
[density ]

1.334±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 100 mg/mL (219.53 mM; Need ultrasonic)
[pka]

7.03±0.20(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard InformationBack Directory
[Uses]

Tolebrutinib is a drug candidate; used in preparation of Dihydroimidazopyridine derivatives for treatment of Bruton''s tyrosine kinase related diseases.
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