ChemicalBook--->CAS DataBase List--->206443-06-3

206443-06-3

206443-06-3 Structure

206443-06-3 Structure
IdentificationBack Directory
[Name]

4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt
[CAS]

206443-06-3
[Synonyms]

4-Methyl-7-[(6-O-sulfo-β-D-galactopyranosyl)oxy]-
4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt
4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate Sodium Salt
4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate sodium salt
4-Methylumbelliferyl β-D-galactopyranoside-6-sulphate sodium salt
4-Methylumbelliferyl β-D-galactopyranoside-6-sulphate sodium salt
[(3R,4S,5S,6S)-3,4,5-trihydroxy-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-2-yl]methyl sulfate
4-Methyl-7-[(6-O-sulfo-beta-D-galactopyranosyl)oxy]-2H-1-benzopyran-2-one monosodium salt
[(3R,4S,5S,6S)-3,4,5-trihydroxy-6-(4-methyl-2-oxo-chromen-7-yl)oxy-tetrahydropyran-2-yl]methoxysulfonyloxysodium
[EINECS(EC#)]

1533716-785-6
[Molecular Formula]

C16H17NaO11S
[MDL Number]

MFCD01861961
[MOL File]

206443-06-3.mol
[Molecular Weight]

440.354
Chemical PropertiesBack Directory
[Melting point ]

196-198?C
[storage temp. ]

-20°C Freezer, Under Inert Atmosphere
[solubility ]

Methanol (Slightly, Sonicated), Water (Slightly)
[form ]

Solid
[color ]

White to Off-White
[Stability:]

-20?C Freezer, Under Inert Atmosphere
Safety DataBack Directory
[HS Code ]

2932209090
Hazard InformationBack Directory
[Description]

4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) (4-MU-Gal-6S) is a fluorogenic substrate used to quantify N-acetylgalactosamine-6-sulphatase (GALNS) activity. 4-MU-Gal-6S is cleaved by GALNS to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. It has been used to detect Morquio disease type A, a lysosomal storage disorder in which GALNS is deficient. 4-MU-Gal-6S can be used to assess GALNS activity in a very small blood volume to determine the extent of deficiency.
[Chemical Properties]

White Solid
[Uses]

4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt is used for the determination of galactose-6-sulphate sulphatase activity,it is used in the diagnosis of Mucopolysaccharidosis IV A.
[Uses]

Used for the determination of galactose-6-sulphate sulphatase activity. Used in the diagnosis of Mucopolysaccharidosis IV A.
[storage]

Store at -20°C
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