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2623-36-1

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2623-36-1 Structure

2623-36-1 Structure
IdentificationBack Directory
[Name]

4-HYDROXYAZOBENZENE-4'-SULFONIC ACID SODIUM SALT
[CAS]

2623-36-1
[Synonyms]

SodiuM 4-Hydroxyazobenzene-4'-sulfonat
SODIUM 4-HYDROXYAZOBENZENE-4'-SULFONATE
Hydroxyazobenzenesulfonicacidsodiumsalt
SodiuM 4-Hydroxyazobenzene-4'-sulfonate Hydrate
4-HYDROXYAZOBENZENE-4'-SULFONIC ACID SODIUM SALT
Sodium4-Hydroxyazobenzene-4'-sulfonateHydrate>
4-HYDROXYAZOBENZENE-4''-SULFONIC ACID SODIUM SALT 98+%
4-(4-Hydroxyphenylazo)benzenesulfonic acid sodium salt
4-HYDROXYAZOBENZENE-4''-SULFONIC ACID SODIUM SALT HYDRATE
Benzenesulfonic acid, 4-[2-(4-hydroxyphenyl)diazenyl]-, sodium salt (1:1)
[Molecular Formula]

C12H9N2NaO4S
[MDL Number]

MFCD00068861
[MOL File]

2623-36-1.mol
[Molecular Weight]

300.27
Chemical PropertiesBack Directory
[Melting point ]

220 °C
[form ]

powder to crystal
[color ]

Light yellow to Brown
Safety DataBack Directory
[Safety Statements ]

26-36/37/39
[HS Code ]

2927.00.5000
[Risk Statements ]

  • 抗癌作用：沙蟾毒精是一种蟾毒内酯类化合物，其能抑制人肝癌细胞 HepG2的黏附、迁移和侵袭，其机制可能与抑制MMP2和MMP9的表达有关。此类化合物具有明显的抗肿瘤作用，可以诱导多种肿瘤细胞凋亡，抑制肿瘤细胞增殖，促进肿瘤细胞分化，耐药逆转，增强免疫等。同时有研究发现，蟾毒内酯类化合物可以抑制血管生成。
  • 抑制血管生成的作用：沙蟾毒精可通过损伤线粒体,使 Cyt  c 释放,进而激活 Caspase,切割PARP,诱导 HUVECs 凋亡。诱导血管内皮细胞周期阻滞及凋亡可能是沙蟾毒精抑制血管生成的重要机制。
Spectrum DetailBack Directory
[Spectrum Detail]

4-HYDROXYAZOBENZENE-4'-SULFONIC ACID SODIUM SALT(2623-36-1)1HNMR
4-HYDROXYAZOBENZENE-4'-SULFONIC ACID SODIUM SALT(2623-36-1)IR1
Hazard InformationBack Directory
[Purification Methods]

Recrystallise it from 95% EtOH.
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