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3754-19-6

3754-19-6 Structure

3754-19-6 Structure
IdentificationBack Directory
[Name]

ambuside
[CAS]

3754-19-6
[Synonyms]

EX 4810
Hydrion
ambuside
RMI 83047
Novohydrin
N-Allyl-4-chloro-6-[(3-hydroxy-2-butenylidene)amino]-1,3-benzenedisulfonamide
[EINECS(EC#)]

223-158-4
[Molecular Formula]

C13H16ClN3O5S2
[MDL Number]

MFCD00867346
[MOL File]

3754-19-6.mol
[Molecular Weight]

393.87
Chemical PropertiesBack Directory
[Melting point ]

205-207°
Hazard InformationBack Directory
[Originator]

Hydrion,Robert and Carriere,France,1970
[Uses]

Ambuside is used in biological studies in the discovery of novel trypanosomicidal drug like chemicals.
[Uses]

Diuretic.
[Definition]

ChEBI: Ambuside is a sulfonamide.
[Manufacturing Process]

Preparation of 2-Allylsulfamyl-4-Sulfamyl-5-Chloro-N-(3-Hydroxy-2- Butenylidene)Aniline or Ambuside: 2-allylsulfamyl-5-chloro-4- sulfamylanilinemonohydrate (6.9 grams, 0.020 mol) was dissolved in 14 ml acetylacetaldehyde dimethylacetal at room temperature and the viscous solution was filtered. Addition of 6 drops of 10:1 H2O/concentrated HCl, and stirring for 20 hours gave a heavy suspension. Dilution with 150 ml of ethanol, collection of the solid, washing twice with 40 ml portions of ethanol, and drying gave 6.2 grams (78%) of product, MP 204-206°C.
[Therapeutic Function]

Diuretic, Antihypertensive
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