ChemicalBook--->CAS DataBase List--->383124-82-1

383124-82-1

383124-82-1 Structure

383124-82-1 Structure
IdentificationBack Directory
[Name]

YE-120
[CAS]

383124-82-1
[Synonyms]

YE-120
2-[3-Cyano-5-(3,4-dichloro-phenyl)-4,5-dimethyl-5H-furan-2-ylidene]-malononitrile
2-[3-Cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]propanedinitrile
[Molecular Formula]

C16H9Cl2N3O
[MOL File]

383124-82-1.mol
[Molecular Weight]

330.17
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble to 100 mM in DMSO
[form ]

Powder
Hazard InformationBack Directory
[Uses]

YE-120 is a GPR35 agonist (EC50 = 32 nM in DMR assays). YE-120 also displays partial agonist activity in a β-arrestin translocation assay (EC50 = 10.2 μM). GPR35 is a Class A, rhodopsin-like G protein-coupled receptor which is predominantly expressed in immune and gastrointestinal tissue, with notable expression in the ileum (rat and human GPR35), the spleen (rat and murine GPR35) and the pancreas (human GPR35).
[storage]

Store at -20°C
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