| Identification | Back Directory | [Name]
PHOSPHATIDYLETHANOLAMINE | [CAS]
39382-08-6 | [Synonyms]
Cephalins
Kephalins
E COLI PE
Cephalinex
l-α-cephalin
Phospholipids cephalins
L-ALPHA-CEPHALIN E COLI
PHOSPHATIDYLETHANOLAMINE
PHOSPHATIDYLCHOLINE(EGG)(RG)
L-3-PHOSPHATIDYLETHANOLAMINE
PhosphatidylethanolamineExEgg
PHOSPHATIDYLETHANOLAMINE (PE)
Glycerophospholipids cephalins
L-α-Phosphatidyleth an olamine
L-LPHA-PHOSPHATIDYLETHANOLAMINE FRO
L-A-PHOSPHATIDYLETHANOLAMINE TYPE IV
3-SN-PHOSPHATIDYLETHANOLAMINE E COLI
L-A-PHOSPHATIDYLETHANOLAMINE TYPE III
L-A-PHOSPHATIDYLETHANOLAMINE TYPE V-A
3-sn-phosphatidylethanolaminesolution
L-A-PHOSPHATIDYLETHANOLAMINE (E COLI)
Phosphatidylethanolamine from soya bean
L-ALPHA-CEPHALIN TYPE V ESCHERICHIA COLI
l-α-phosphatidylethanolamine from egg yolk
3-SN-PHOSPHATIDYLETHANOLAMINE FROM E. CO LI
PHOSPHATIDYLETHANOLAMINE ISO 9001：2015 REACH
L-alpha-Phosphatidylethanolamine from egg yolk
l-α-phosphatidylethanolamine from escherichia coli
L-A-PHOSPHATIDYLETHANOLAMINE TYPE IV:*FR OM SOYBEAN
L-A-PHOSPHATIDYLETHANOLAMINE*TYPE VII-A FROM BOVINE
L-A-PHOSPHATIDYLETHANOLAMINE TYPE VII:*F ROM BOVINE
L-ALPHA-PHOSPHATIDYLETHANOLAMINE SOLUTION, EGG YOLK
3-sn-Phosphatidylethanolamine solution,L-α-Cephalin
L-A-PHOSPHATIDYLETHANOLAMINE TYPE III:*F ROM EGG YOL
L-A-PHOSPHATIDYLETHANOLAMINE TYPE V*FROM ESCHERICHI
3-SN-PHOSPHATIDYLETHANOLAMINE SOLUTION, FROM SOYBEAN
L-A-PHOSPHATIDYLETHANOLAMINE TYPE IX*FRO M ESCHERICH
L-A-PHOSPHATIDYLETHANOLAMINE TYPE III*FR OM EGG YOLK
L-A-PHOSPHATIDYLETHANOLAMINE TYPE VII*FR OM BOVINE L
3-SN-PHOSPHATIDYLETHANOLAMINE SOLUTION, FROM EGG YOLK
l-α-phosphatidylethanolamine from glycine max (soybean)
L-ALPHA-PHOSPHATIDYLETHANOLAMINE TYPE V ESCHERICHIA COLI
Phosphatidylethanolamine (100 mg) (COLD SHIPMENT REQUIRED)
1,2-Diacyl-sn-glycero-3-phosphoethanolamine, L-α-Cephalin
L-alpha-Phosphatidylethanolamine from Glycine max (soybean)
1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE TYPE V ESCHERICHIA COLI
Phosphatidylethanolamine (100 mg) (INTERNATIONAL COLD CHAIN SHIPMENT REQUIRED)
[(2R)-1-[2-azanylethoxy(hydroxy)phosphoryl]oxy-3-pentadecanoyloxy-propan-2-yl] icosanoate
1,2-Diacyl-sn-glycero-3-phosphoethanolamine, 3-sn-Phosphatidylethanolamine, L-α-Cephalin
arachidic acid [(1R)-1-[[2-aminoethoxy(hydroxy)phosphoryl]oxymethyl]-2-pentadecanoyloxy-ethyl] ester
L-α-Phosphatidylethanolamine from egg yolk,1,2-Diacyl-sn-glycero-3-phosphoethanolamine, L-α-Cephalin
(18R,21S)-24-Amino-21-hydroxy-21-oxido-15-oxo-16,20,22-trioxa-21λsup5sup-phosphatetracosan-18-ylicosanoate
L-α-Phosphatidylethanolamine from Glycine max (soybean),1,2-Diacyl-sn-glycero-3-phosphoethanolamine, L-α-Cephalin
L-α-Phosphatidylethanolamine from Escherichia coli,1,2-Diacyl-sn-glycero-3-phosphoethanolamine, 3-sn-Phosphatidylethanolamine, L-α-Cephalin | [EINECS(EC#)]
254-438-4 | [Molecular Formula]
C41H78NO8P | [MDL Number]
MFCD00146358 | [MOL File]
39382-08-6.mol | [Molecular Weight]
744.034 |
| Chemical Properties | Back Directory | [density ]
approximate 1.47g/ml(20℃) | [storage temp. ]
−20°C
| [solubility ]
chloroform: 50 mg/mL, slightly hazy, brown-yellow
| [form ]
solution
|
| Hazard Information | Back Directory | [Uses]
L-α-Phosphatidylethanolamine from egg yolk has been used:
- as a component of lipid mixture for the synthesis of giant unilamellar vesicles (GUVs)
- in ceramide phosphoethanolamine (CPE) synthase assay using crude sphingomyelin synthase-related protein from Hela cells
- for the standard curve generation for the quantification of lipids in plantaris muscle homogenates from mice
| [General Description]
L-α-Phosphatidylethanolamine from egg yolk has high unsaturated fatty acid content and elicits radical-scavenging activity. L-α-Phosphatidylethanolamine (PE) is a membrane phospholipid and is interconverted to phosphotidylserine in the presence of phosphatidylserine synthase 2. PE is essential for maintaining the structural integrity of membranes. It is the second most abundant phospholipid in animals, plants and yeast and the major lipid in bacteria. It is synthesized in mitochondria in mammals. | [Enzyme inhibitor]
This hygroscopic phospholipid, also called cephalin and 1,2-diacyl-sn-
glycero-3-phosphoethanolamine, is an important constituent of
biomembranes and lipoproteins. It is the major structural phospholipid in
brain tissue. The physical properties depend on the nature of the acyl groups
and on the presence of other lipids. Freshly prepared
phosphatidylethanolamines are white solids that turn yellow and brown on
exposure to air. They typically sinter between 80 and 90°C and melt in the
neighborhood of 175°C. Solutions of phosphatidylethanolamine slowly
decompose at room temperature (roughly 0.3-0.5% per day); hence,
solutions should always be freshly prepared and kept cold prior to use. It is
labile in alkaline conditions. See also specific compound Target (s) : b-
N-acetylglucosaminyl-glycopeptide b-1,4-galactosyltransferase; N-
acetyllactosamine synthase; acylglycerol kinase, or monoacylglycerol
kinase; cholesterol monooxygenase, side-chain-cleaving, or CYP11A1
; chymase; cytidylate cyclase; dolichyldiphosphatase;
dolichyl-phosphatase; dopamine b-monooxygenase;
ethanolaminephosphotransferase; glutamate dehydrogenase; g-
glutamyl transpeptidase, mildly inhibited; glycerol-3-phosphate O-
acyltransferase; glycerone-phosphate O-acyltransferase, or
dihydroxyacetione-phosphate O-acyltransferase; hormone-sensitive
lipase; 3-hydroxybutyrate dehydrogenase; indole-3-acetate b-
glucosyltransferase; phosphatidate cytidylyltransferase; 1-
phosphatidylinositol 4-kinase; phosphoinositide phospholipase C
; phospholipase D, phosphatidylcholine-specific enzyme;
sphingomyelin phosphodiesterase; steryl-b-glucosidase; UDP-N-
acetylglucosamine:dolichyl-phosphate N-acetylglucosaminephosphotrans-ferase. | [Purification Methods]
Purify the cephalin by dissolving it in EtOH, adding Pb(OAc)2.3H3O (30g in 100mL H2O) until excess Pb2+ is present. Filter off the solid. Pass CO2 gas through the solution until precipitation of PbCO3 ceases. Filter the solid off and evaporate (while bubbling CO2) under vacuum. An equal volume of H2O is added to the residual oil and extracted with hexane. The hexane extract is washed with H2O until the aqueous phase is free from Pb [test with dithizone (2 mg in 100 mL CCl4; Feigel Spot Tests Vol I, Elsevier p. 10 1954)]. The hexane is dried (Na2SO4), filtered and evaporated to give a yellow waxy solid which should be dried to constant weight in vacuo. It is practically insoluble in H2O and Me2CO, but freely soluble in CHCl3 (5%) and Et2O, and slightly soluble in EtOH. [Schofield & Dutton Biochemical Preparations 5 5 1957.] |
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