| Identification | Back Directory | [Name]
MITRAGYNINE PICRATE | [CAS]
4098-40-2 | [Synonyms]
Mitragynin
mitragynine
MITRAGYNINE(P)
Mitragynine RM
MITRAGYNINE(AS)
MITRAGYNINE(SH)
Mitragynine (CRM)
Mitragynine, >=98%
MITRAGYNINE PICRATE
Mitragynine solution
9-Methoxycorynantheidine
Mitragynin hydrochloride
Mitragynine (100μg/ML in Methanol)
16,17-Didehydro-9,17-diMethoxy-corynan-16-carboxylic Acid Methyl Ester
(16E,20β)-16,17-Didehydro-9,17-dimethoxycorynan-16-carboxylic acid methyl ester
(16E,20beta)-16,17-Didehydro-9,17-dimethoxy-corynan-16-carboxylic acid methyl ester
(E)-Methyl 2-((2S,3S,12bS)-3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinoliz
(E)-Methyl 2-((2S,3S,12bS)-3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-
(E)-Methyl 2-((2S,3S,12bS)-3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl)-3-methoxyacrylate
(αE,2S,3S,12bS)-3-Ethyl-1,2,3,4,6,7,12,12b-octahydro-8-Methoxy-α-(MethoxyMethylene)-indolo[2,3-a]quinolizine-2-acetic Acid Methyl Ester
Indolo[2,3-a]quinolizine-2-acetic acid, 3-ethyl-1,2,3,4,6,7,12,12b-octahydro-8-methoxy-α-(methoxymethylene)-, methyl ester, (αE,2S,3S,12bS)- | [EINECS(EC#)]
200-659-6 | [Molecular Formula]
C29H33N5O11 | [MDL Number]
MFCD00189432 | [MOL File]
4098-40-2.mol | [Molecular Weight]
627.6 |
| Chemical Properties | Back Directory | [Melting point ]
92-95°C | [alpha ]
D +39° (chloroform) | [Boiling point ]
bp5 230-240° | [density ]
1.22±0.1 g/cm3 (20 ºC 760 Torr) | [Fp ]
9℃ | [storage temp. ]
-20°C Freezer | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
18.35±0.60(Predicted) | [color ]
Light Orange to Dark Beige to Very Dark Yellow |
| Hazard Information | Back Directory | [Description]
This alkaloid has been isolated from Mitragyna speciosa Korth, and is amorphous
although it yields a series of crystalline salts and derivatives. The hydrochloride
crystallizes as colourless leaflets from EtOH-Et20 with m.p. 243°C; the picrate
forms thin, orange-red needles, m.p. 223-4°C and the methiodide is a pale
yellow powder which, although amorphous, has a sharp melting point of
21 1. 5°C. The alkaloid also forms compounds with acetic acid, m.p. 142°C,
decomposing at 175-6°, and with trichloroacetic acid, m.p. 157°C.
Mitragynine exerts a general depressant effect on plain muscle and facilitates
the passage of autonomic impulses. It is, however, ineffective against pathogenic
organisms. | [Chemical Properties]
White to Off-White Solid | [Uses]
A neurochemical, having both stimulant and opiate-like effects depending on the dosage. Currently, Mitragynin is being investigated for its ability to treat hard drug addiction. | [Uses]
Mitragynine is a neurochemical, having both stimulant and opiate-like effects depending on the dosage. Currently, Mitragynine is being investigated for its ability to treat hard drug addiction. | [Definition]
ChEBI: Mitragynine is a monoterpenoid indole alkaloid. | [References]
Field., J. Chern. Soc., 119,887 (1921)
Raymond-Hamet, Millat., Bull. sci. pharrnacol., 40, 593 (1933)
lng, Raison., J. Chern. Soc., 986 (1939)
Loudon., Chern. Soc. Spec. Publ., 3, 12 (1955)
Hendrickson., Chern. & Ind., 713 (1961)
Joshi, Raymond-Hamet, Taylor., ibid, 573 (1963)
Pharmacology:
Grewal., J. Pharrn. expo Ther., 46,251 (1932) |
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