| Identification | Back Directory | [Name]
polymyxin B(1) | [CAS]
4135-11-9 | [Synonyms]
polymyxin B(1)
(-)-N2-[[(6S)-6-Methyloctanoyl]-L-A2bu-L-Thr-L-A2bu-]cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-)
(6S)-N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methyloctanamide | [Molecular Formula]
C56H98N16O13 | [MDL Number]
MFCD01699017 | [MOL File]
4135-11-9.mol | [Molecular Weight]
1203.48 |
| Chemical Properties | Back Directory | [Boiling point ]
838.79°C (rough estimate) | [density ]
1.0500 (rough estimate) | [refractive index ]
1.6200 (estimate) | [storage temp. ]
Store at -20°C | [solubility ]
PBS (pH 7.2): 2 mg/ml | [form ]
A crystalline solid |
| Hazard Information | Back Directory | [Uses]
An antibacterial compound. It has a high volume of distribution and longer elimination half-life in patient with multidrug-resistant gram-negative bacterial infection. | [Definition]
ChEBI: A polymyxin having a (6R)-6-methyloctanoyl group at the amino terminus. |
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