| Identification | Back Directory | [Name]
DL-THREO-2-ACETAMIDO-L-(4-NITROPHENYL)-L,3-PROPANEDIOL | [CAS]
4423-58-9 | [Synonyms]
Corynecin Ⅰ
DechlorochloraMphenicol, DidechloraMphenicol
DL-THREO-2-ACETAMIDO-L-(4-NITROPHENYL)-L,3-PROPANEDIOL
Acetamide, N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]- | [Molecular Formula]
C11H14N2O5 | [MOL File]
4423-58-9.mol | [Molecular Weight]
254.24 |
| Hazard Information | Back Directory | [Description]
Corynecin I is a chloramphenicol-like antibiotic originally isolated from Corynebacterium. It is active against Gram-positive and Gram-negative bacteria with MIC values of 5.2-83 μg/ml for S. sonnei, P. vulgaris, K. pneumoniae, and S. aureus among others. | [Uses]
Corynecin I is a chloramphenicol-like acyl nitrophenylpropylamine. | [Uses]
Corynecin I is a member of a naturally-occurring complex of chloramphenicol-like acyl nitrophenylpropylamines isolated from Corynebacterium hydrocarboclastus in 1972. Corynecin I is active against Gram positive and Gram negative bacteria. Although less potent than chloramphenicol, corynecin I shows a similar species selectivity. | [storage]
Store at -20°C |
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