ChemicalBook--->CAS DataBase List--->451492-95-8

451492-95-8

451492-95-8 Structure

451492-95-8 Structure
IdentificationBack Directory
[Name]

MP-412
[CAS]

451492-95-8
[Synonyms]

AV-412
MP-412
CS-2307
MP-412 free base
AV-412 (free base)
AV-412 free base (MP-412 free base)
AV-412;MP-412;AV 412;MP 412;AV412;MP412
N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(3-methyl-3-(4-methylpiperazin-1-yl)but-1-yn-1-yl)quin
N-[4-(3-chloro-4-fluoroanilino)-7-[3-methyl-3-(4-methylpiperazin-1-yl)but-1-ynyl]quinazolin-6-yl]prop-2-enamide
N-(4-((3-chloro-4-fluorophenyl)amino)-7-(3-methyl-3-(4-methylpiperazin-1-yl)but-1-yn-1-yl)quinazolin-6-yl)acrylamide
N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-methyl-3-(4-methyl-1-piperazinyl)-1-butyn-1-yl]-6-quinazolinyl]-2-propenamide
2-PropenaMide, N-[4-[(3-chloro-4-fluorophenyl)aMino]-7-[3-Methyl-3-(4-Methyl-1-piperazinyl)-1-butyn-1-yl]-6-quinazolinyl]-
[Molecular Formula]

C27H28ClFN6O
[MDL Number]

MFCD16038939
[MOL File]

451492-95-8.mol
[Molecular Weight]

507
Chemical PropertiesBack Directory
[Boiling point ]

672.9±55.0 °C(Predicted)
[density ]

1.33
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: ≥ 50 mg/mL (98.62 mM)
[form ]

Powder
[pka]

11.61±0.43(Predicted)
Hazard InformationBack Directory
[Uses]

AV 412 is used in the synthetic preparation of phenylaminoquinazoline derivatives as inhibitors of tyrosine-specific protein kinase for preparation and/or treatment of cancers, diseases caused by arteriosclerosis, or psoriasis.
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