| Identification | Back Directory | [Name]
marinobufagenin | [CAS]
470-42-8 | [Synonyms]
Marinobufagin
Marinobufogenin
marinobufagenin
3β,5β-Dihydroxy-14β,15β-epoxybufa-20,22-dienolide
14,15β-Epoxy-3β,5-dihydroxy-5β-bufa-20,22-dienolide
3β,5-Dihydroxy-14,15β-epoxy-5β-bufa-20,22-dienolide
(3β,5β,15β)-3,5-Dihydroxy-14,15-epoxybufa-20,22-dienolide
Bufa-20,22-dienolide, 14,15-epoxy-3,5-dihydroxy-, (3β,5β,15β)- | [Molecular Formula]
C24H32O5 | [MDL Number]
MFCD32661898 | [MOL File]
470-42-8.mol | [Molecular Weight]
400.52 |
| Chemical Properties | Back Directory | [Melting point ]
224-225 °C | [Boiling point ]
589.0±50.0 °C(Predicted) | [density ]
1.31±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 3 mg/ml; DMF:PBS (pH 7.2) (1:8): 0.1 mg/ml; Ethanol: 1 mg/ml | [form ]
A crystalline solid | [pka]
14.77±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
Marinobufagin is a bufadienolide with anti-gastric cancer effect. A bioactive steroid that also functions as an endogenous Na/K-ATPase bufadienolide inhibitor that plays a major role in human cardiovascular diseases. | [Definition]
ChEBI: Marinobufagenin is a cardiotonic steroid secreted by the toad Bufo rubescens and other related species such as Bufo marinus. An endogenous Na/K-ATPase inhibitor, it is a vasoconstrictor with effects similar to digitalis. It has a role as an EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor and an epitope. It is a steroid hormone and an epoxy steroid. It is functionally related to a (5beta)-bufadienolide. |
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| Company Name: |
WG reagent
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13391486464 |
| Website: |
www.wgchemical.com |
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