ChemicalBook--->CAS DataBase List--->483-15-8

483-15-8

483-15-8 Structure

483-15-8 Structure
IdentificationBack Directory
[Name]

dihydroberberine
[CAS]

483-15-8
[Synonyms]

Nsc331264
Dihydroberbine
dihydroberberine
DihydrouMbellatine
Berberine Dihydro Impurity
Dihydroberberine/Dihydroumbellatine
9,10-Dimethoxy-2,3-(methylenedioxy)-13,13a-didehydrob
9,10-Dimethoxy-2,3-(methylenedioxy)-13,13a-didehydroberbine
5,8-Dihydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine
6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine, 5,8-dihydro-9,10-dimethoxy-
9,10-DiMethoxy-6,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinoline
[Molecular Formula]

C20H19NO4
[MOL File]

483-15-8.mol
[Molecular Weight]

337.37
Chemical PropertiesBack Directory
[Melting point ]

223-224℃ (dec.)
[Boiling point ]

557.8±50.0 °C(Predicted)
[density ]

1.37±0.1 g/cm3 (20 ºC 760 Torr)
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

Soluble in DMSO
[form ]

crystals
[pka]

3.08±0.20(Predicted)
[color ]

Yellow
[Water Solubility ]

Soluble to 57.46 mg/l in water
Safety DataBack Directory
[Symbol(GHS) ]


GHS07,GHS02
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H226
[Precautionary statements ]

P501-P270-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P303+P361+P353-P332+P313-P301+P312+P330-P403+P235
Hazard InformationBack Directory
[Uses]

Dihydroberberine is a derivative Berberine (B318150), an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells.
[Definition]

ChEBI: Lambertine is an alkaloid.
[storage]

Store at -20°C,sealed storage, away from moisture and light
Spectrum DetailBack Directory
[Spectrum Detail]

dihydroberberine(483-15-8)1HNMR
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