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ChemicalBook--->CAS DataBase List--->57568-80-6

57568-80-6

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57568-80-6 Structure

57568-80-6 Structure
IdentificationBack Directory
[Name]

PNU 37883 hydrochloride
[CAS]

57568-80-6
[Synonyms]

U-37883A
PNU 37883 hydrochlor
PNU 37883 HYDROCHLORIDE
N-CYCLOHEXYL-N'-TRICYCLO[3.3.1.1(3,7)]DEC-1-YL-4-MORPHOLINECARBOXIMIDAMIDE HYDROCHLORIDE
[Molecular Formula]

C21H36ClN3O
[MDL Number]

MFCD03840615
[MOL File]

57568-80-6.mol
[Molecular Weight]

381.98
Chemical PropertiesBack Directory
[RTECS ]

QD9865500
[storage temp. ]

2-8°C
[solubility ]

DMSO: ~23 mg/mL
[form ]

powder
[color ]

white
Safety DataBack Directory
[Safety Statements ]

22-24/25
[WGK Germany ]

3
Hazard InformationBack Directory
[Biological Activity]

Novel antagonist selective for the vascular form of K ATP channel; inhibits K ATP currents in isolated mesenteric artery smooth muscle cells (K d = 65 nM) but not in cardiac or skeletal myocytes. In vivo, inhibits blood vessel relaxation and hypotension induced by pinacidil. Displays weak diuretic effects.
[storage]

Desiccate at RT
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