ChemicalBook--->CAS DataBase List--->636-65-7

636-65-7

636-65-7 Structure

636-65-7 Structure
IdentificationBack Directory
[Name]

L-ISOGLUTAMINE
[CAS]

636-65-7
[Synonyms]

Glu-NH2
L-Glu-NH2
H-GLU-NH2
H-ISOGLN-OH
H-L-Glu-NH2
H-GLU-NH2 HCL
L-ISOGLUTAMINE
GLUTAMIC ACID-NH2
L-GLUTAMIC ACID AMIDE
L-Glutamic acid α-amide
L-GLUTAMIC ACID ALPHA-AMIDE
H-Isogln-OH, L-IsoglutaMine
L-ISOGLUTAMINE HYDROCHLORIDE
3-(Carboxymethyl)alaninamide
(4S)-4,5-diamino-5-oxopentanoicaci
(S)-4,5-Diamino-5-oxopentanoic acid
(4S)-4,5-diamino-5-oxopentanoic acid
(4S)-4-amino-4-carbamoylbutanoic acid
L-Glutamic acid alpha-amide USP/EP/BP
Pentanoic acid, 4,5-diamino-5-oxo-, (4S)-
L-GLUTAMIC ACID ALPHA-AMIDE HYDROCHLORIDE
L-Glutamic acid α-amide≥ 98% (Assay by Titration)
[Molecular Formula]

C5H10N2O3
[MDL Number]

MFCD00135661
[MOL File]

636-65-7.mol
[Molecular Weight]

146.14
Chemical PropertiesBack Directory
[Melting point ]

160 °C
[alpha ]

D21 +20.5° (c = 6.1 in H2O)
[Boiling point ]

423.1±40.0 °C(Predicted)
[density ]

1.321±0.06 g/cm3(Predicted)
[storage temp. ]

−20°C
[solubility ]

Water (Sparingly)
[form ]

Solid
[pka]

pK1 3.81; pK2 7.88(at 25℃)
[color ]

White to Off-White
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Chemical Properties]

White to off-white powder
[Definition]

ChEBI: L-isoglutamine is an isoglutamine that has L-configuration. It is an isoglutamine and a L-glutamic acid derivative. It is an enantiomer of a D-isoglutamine.
Questions And AnswerBack Directory
[Preparation]

N-CBZ-γ-benzyl-L-isoglutamine (5 gm.) was dissolved in 100 ml. of 50% ethanol and hydrogenated for 12 hr. at room temperature and atmospheric pressure in the presence of palladium catalyst (5% Pd on calcium carbonate). The catalyst was filtered off and a trace of calcium ions was removed with oxalic acid. The solution was evaporated to dryness, the residue dissolved in a small amount of hot water, and the solution treated with charcoal. Alcohol was added to the cloud point and L-isoglutamine was recovered from the chilled solution as fine white crystals, m.p. 186-188°, yield 65%.
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