| Identification | Back Directory | [Name]
BAY 58-2667 hydrochloride | [CAS]
646995-35-9 | [Synonyms]
Cinaciguat HCl
Cinaciguat (hydrochloride)
Cinaciguat hydrochloride >=98% (HPLC)
BAY 58-2667 hydrochloride - Cinaciguat hydrochloride
4-[[(4-Carboxybutyl)[2-[2-[[4-(2-phenylethyl)phenyl]methoxy]phenyl]ethyl]amino]methyl]benzoic acid hydrochloride | [Molecular Formula]
C36H40ClNO5 | [MDL Number]
MFCD28127267 | [MOL File]
646995-35-9.mol | [Molecular Weight]
602.17 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
DMSO:66.74(Max Conc. mg/mL);110.83(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);0.83(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);49.82(Max Conc. mM)
Ethanol:5.0(Max Conc. mg/mL);8.3(Max Conc. mM) | [form ]
powder | [color ]
white to beige |
| Hazard Information | Back Directory | [Biochem/physiol Actions]
Cinaciguat activates sGC (soluble guanylate cyclase) independently of NO. Cinaciguat binds to sGC′s NO-sensory H-NOX domain when it is heme-depleted. Also, the compound Cinaciguat protects sGC from oxidation-induced ubiquitin-triggered degradation. | [storage]
Store at -20°C |
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