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716-61-0

716-61-0 Structure

716-61-0 Structure
IdentificationBack Directory
[Name]

D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
[CAS]

716-61-0
[Synonyms]

levoamine
Chloromycin base
L-BASE (AMINODIOL)
chloramphenicolbase
CHLORAMPHENICOL-WATER SOLUBLE
D(-)Threo-1-(4-nitro-phenyl)-2
CHLORAMPHENICOL BASE CRYSTALLINE
(R,R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol
(1R,2R)-1-(4-Nitrophenyl)-2-aminopropane-1,3-diol
D-THREO-(-)-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANE
(1R,2R)-2-AMINO-1-(4-NITROPHENOL)PROPANE-1,3-DIOL
(1R,2R)-2-AMINO-1-(4-NITROPHENYL)PROPANE-1,3-DIOL
(1R,2R)-(-)-2-AMINO-1-NITROPHENYL)-1,3-PROPANEDIOL
2-amino-1-(p-nitrophenyl)-3-propanediod-threo-(-)-
D-(-)threo-2-amino-1-(p-nitrophenyl)propane-1,3-diol
D(-)THREO-1-(4-NITRO-PHENYL)-2-AMINO-1,3-PROPANEDIOL
d-threo-(-)-2-amino-1-(p-nitrophenyl)-1,3-propanediol
D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
(1R,2R)-(-)-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
1,3-Propanediol, 2-amino-1-(4-nitrophenyl)-, (1R,2R)-
[1R,2R,(-)]-2-Amino-1-(p-nitrophenyl)-1,3-propanediol
(1R,2R)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol,96%
(1R,2R)-(-)-2-AMINO-1-ITROPHENYL)-1,3-PR OPANEDIOL,99%
(1R,2R)-(-)-2-AMino-1-(4-nitrophenyl)-1,3-propanediol 99%
(1R,2R)-2-AMino-1-(4-nitrophenyl)propane-1,3-diol, 96% 5GR
(1R,2R)-(-)-2-AMino-1-(4-nitrophenyl)-1,3-propanediol, 96%, 96%
(1R,2R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol hydrochloride
(1R,2R)-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol≥ 99% (by Assay)
D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
Chloramphenicol base, D-(-)-threo-2-Amino-1-(p-nitrophenyl)-1,3-propanediol
(1R,2R)-()-2-Amino-1-(4-nitrophenyl)-1,3-propanediol,D-()-threo-2-Amino-1-(p-nitrophenyl)-1,3-propanediol, Chloramphenicol base
[EINECS(EC#)]

211-938-7
[Molecular Formula]

C9H12N2O4
[MDL Number]

MFCD00078126
[MOL File]

716-61-0.mol
[Molecular Weight]

212.2
Chemical PropertiesBack Directory
[Appearance]

light yellow powder
[Melting point ]

163-165 °C(lit.)
[Boiling point ]

352.03°C (rough estimate)
[density ]

1.3136 (rough estimate)
[refractive index ]

-30.5 ° (C=1, 6mol/L HCl)
[storage temp. ]

−20°C
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[Water Solubility ]

almost transparency in hot Water
[form ]

Powder
[pka]

10.98±0.45(Predicted)
[color ]

Light yellow
[optical activity]

[α]25/D 30°, c = 1 in 6 M HCl
[InChIKey]

OCYJXSUPZMNXEN-RKDXNWHRSA-N
Hazard InformationBack Directory
[Chemical Properties]

light yellow powder
[Uses]

D-threo-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol is an impurity of Chloramphenicol (C325030), a broad spectrum antibiotic agent obtained from cultures of the soil bacterium Streptomyces venezuel ae.
[Uses]

Chloramphenicol base is the parent 4-nitrophenylpropylamine formed by the hydrolysis of the dichloroacetamide of chloramphenicol and is a degradation product commonly encountered with commercial production of chloramphenicol. Chloramphenicol base has no antibiotic activity but has played an integral role in the synthesis and SAR of new generation antibiotics, notably thiamphenicol and experimental analogues, bromamphenicol and methamphenicol.
[Definition]

ChEBI: A diol that is propane 1,3-diol bearing additional amino and 4-nitrophenyl substituents at positions 2 and 1 respectively.
Safety DataBack Directory
[Hazard Codes ]

Xn,T
[Risk Statements ]

22-36/37/38-45
[Safety Statements ]

26-45-53-22
[RIDADR ]

UN 3259 8/PG 3
[WGK Germany ]

3
[RTECS ]

TY3100000
[HS Code ]

29221990
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Propiophenone
[Preparation Products]

Potassium heptadecafluoro-1-octanesulfonate
Spectrum DetailBack Directory
[Spectrum Detail]

D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL(716-61-0)MS
D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL(716-61-0)1HNMR
D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL(716-61-0)IR1
D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL(716-61-0)IR2
D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL(716-61-0)Raman
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