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ChemicalBook--->CAS DataBase List--->77668-69-0

77668-69-0

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77668-69-0 Structure

77668-69-0 Structure
IdentificationBack Directory
[Name]

N-Me-L-Ala-maytansinol
[CAS]

77668-69-0
[Synonyms]

AP3 Intermidate
AP3 Intermidate 1
N-Me-L-Ala-maytansinol
Maytansine, N2'-deacetyl-
maytansinol 3-(S)-α-N-methylaminopropionate
[EINECS(EC#)]

604-604-1
[Molecular Formula]

C32H44ClN3O9
[MDL Number]

MFCD32263382
[MOL File]

77668-69-0.mol
[Molecular Weight]

650.16
Chemical PropertiesBack Directory
[Boiling point ]

849.5±65.0 °C(Predicted)
[density ]

1.31±0.1 g/cm3(Predicted)
[pka]

9.82±0.70(Predicted)
Hazard InformationBack Directory
[Description]

Maytansinoid-Ala is a potent microtubule-targeted compound that inhibits proliferation of cells at mitosis. Maytansinoid-Ala can be used for synthesis of ADCs. The microtubule-targeting maytansinoids accumulate in cells and induce mitotic arrest at 250- to 1000-fold lower concentrations than those required for their association with tubulin or microtubules.
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