ChemicalBook--->CAS DataBase List--->80714-61-0

80714-61-0

80714-61-0 Structure

80714-61-0 Structure
IdentificationBack Directory
[Name]

ACTH (4-7), Pro-Gly-Pro-
[CAS]

80714-61-0
[Synonyms]

Semax
lemod solu
SemaxAcetate
Peptides Semax
prednol [inj.]
ACTH (4-7), Pro-Gly-Pro-
Met-Glu-His-Phe-Pro-Gly-Pro
(PRO8,GLY9,PRO10)ACTH-(4-10)
ACTH (4-7), Pro-Gly-Pro- ISO 9001:2015 REACH
ACTH (4-7), Pro-Gly-Pro trifluoroacetate salt
L-METHIONYL-L-Α-GLUTAMYL-L-HISTIDYL-L-PHENYLALANYL-L-PROLYLGLYCYL-L-PROLINE
L-Proline, L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-prolylglycyl-
L-Methionyl-L-a-glutamyl-L-histidyl-L-phenylalanyl-L-prolylglycyl-L-proline trifluoroacetate salt
succinic acid, 21-monoester with 11beta,17,21-trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione, monosodium s...
[EINECS(EC#)]

253-368-1
[Molecular Formula]

C37H51N9O10S
[MDL Number]

MFCD04113563
[MOL File]

80714-61-0.mol
[Molecular Weight]

813.92
Chemical PropertiesBack Directory
[Boiling point ]

1335.2±65.0 °C(Predicted)
[density ]

1.391±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C
[solubility ]

H2O: >2mg/mL
[form ]

powder
[pka]

3.43±0.20(Predicted)
[color ]

white to tan
[Water Solubility ]

Soluble to 2 mg/ml in water
[Sequence]

H-Met-Glu-His-Phe-Pro-Gly-Pro-OH
[InChIKey]

AFEHBIGDWIGTEH-YNWVLKOQNA-N
[SMILES]

N1(CCC[C@H]1C(=O)NCC(=O)N1CCC[C@H]1C(=O)O)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CCSC)CC1N=CNC=1)CC1=CC=CC=C1 |&1:4,15,21,25,29,38,r|
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Description]

Semax is a synthetic analogue of the adrenocorticotropic hormone, a hormone responsible for the production of cortisol which in turn regulates glucose and lipid metabolism and helps to maintain blood pressure. In the hippocampus, Semax rapidly elevates the levels of brain-derived neurotrophic factor (BDNF), a protein important in encouraging growth and differentiation of new neurons and synapses. BDNF is active in the hippocampus, cortex, and forebrain and is important for memory, coordination, concentration, and learning. Semax also works to activate the dopaminergic and serotonergic systems to help prime the brain for action and to induce a controlled state of mental stress.
[benefits]

Over continued use, guests have seen benefits such as:Reduces anxiety and depression;Improves mental clarity, memory, and focus
[Biological Functions]

Semax altered the expression of genes that modulate the amount and mobility of immune cells. It also could enhanced the expression of genes that encode chemokines and immunoglobulins. It can increase attention and short-term memory, improve Non-proliferative Diabetic Neuropathy, and can help during recovery from Stroke/Hypoxia
[Mechanism of action]

Semax has been prescribed for anxiety, memory improvement, ischemic events, stroke, nerve regeneration, ADHD, opioid withdrawal and even chronic diseases such as ALS, Parkinson’s Disease, and Alzheimer’s. Semax has been known to be used as an Adderall alternative.
[Uses]

Semax has been prescribed for anxiety, memory improvement, ischemic events, stroke, nerve regeneration, ADHD, opioid withdrawal and even chronic diseases such as ALS, Parkinson’s Disease, and Alzheimer’s. Semax has been known to be used as an Adderall alternative.
[Clinical Use]

Semax has undergone extensive study in Russia and is on the Russian List of Vital & Essential Drugs approved by the Russian Federation government on December 7, 2011. Medical uses for Semax include treatment of stroke, transient ischemic attack, memory and cognitive disorders, peptic ulcers, optic nerve disease, and to boost the immune system.
[storage]

Store at -20°C
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