| Identification | Back Directory | [Name]
CONCANAMYCIN B | [CAS]
81552-33-2 | [Synonyms]
S 45B
MCH 210
CONCANAMYCIN B
ConcanaMycin B (high purity)
8-Deethyl-8-methylconcanamycin A | [Molecular Formula]
C45H73NO14 | [MDL Number]
MFCD01731919 | [MOL File]
81552-33-2.mol | [Molecular Weight]
852.06 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble | [form ]
White to off-white solid. | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Concanamycin B is a macrocyclic lactone originally isolated from Streptomyces diastatochromogenes in 1982 as a potent inhibitor of the proliferation of mouse splenic lymphocytes stimulated by concanavalin A. Like other concanamycins and bafilomycins, concanamycin B inhibits vacuolar H(+)-ATPase. Concanamycin B inhibits the expression of newly-synthesized MHC class II molecules and suppresses bone resorption in vitro. | [Uses]
Concanamycin B is an antibiotic and inhibitor of vacuolar-type H+-ATPase. | [storage]
+4°C |
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