| Identification | Back Directory | [Name]
HUMAN M-CSF | [CAS]
81627-83-0 | [Synonyms]
csf-1
M-CSF
MGI-IM
mCSF-1
mM-CSF
RHM-CSF
MGC31930
M-CSF rat
Lanimostim
HUMAN M-CSF
HUMAN CSF-1
HUMAN MGI-IM
M-CSF, HUMAN
M-CSF from rat
M-CSF from mouse
NATURAL HUMAN CSF-1
NATURAL HUMAN M-CSF
RECOMBINANT HUMAN M-CSF
colony-stimulatingfactor1
monocytecolony-stimulatingfactor
MACROPHAGE COLONY STIMULATING FACTOR
Recombinant Human M-CSF, HUMAN M-CSF
Macrophage colony-stimulating factor 1
HUMAN MACROPHAGE COLONY STIMULATING FACTOR
Recombinant Rat M-Csf/Csf1 Protein, No Tag
MACROPHAGE COLONY STIMULATING FACTOR, HUMAN
Recombinant Mouse M-Csf/Csf1 Protein, No Tag
cytokines,macrophagecolony-stimulatingfactor
Recombinant Human M-CSF/CSF1 Protein, His Tag
macrophagehumanrecombinantexpressedinyeast95+%
macrophage colony-stimulating factor from mouse
ANTI-M-CSF (CENTER) antibody produced in rabbit
Monoclonal Anti-CSF1 antibody produced in mouse
Processed macrophage colony-stimulating factor 1
MACROPHAGE COLONY STIMULATOR FACTOR (M-CSF) HUMAN
NATURAL HUMAN MACROPHAGE-COLONY STIMULATING FACTOR
Macrophage Colony-StimulatingFactor, Human, Recomb.
FOR USE IN THE MANUFACTURE OF MEDICAMENTS OF HS NO. 3002
MACROPHAGE COLONY-STIMULATING FACTOR, HUMAN, RECOMBINANT
Macrophage Colony-Stimulating Factor, Human, Recombinant, E. coli
MACROPHAGE-COLONY STIMULATING FACTOR, HU MAN RECOMBINANT EXPRESSED IN E. COLI | [MDL Number]
MFCD00241918 |
| Hazard Information | Back Directory | [Uses]
Macrophage Colony-Stimulating Factor from mouse has been used:
- in the initiation of osteoclastogenesis in bone marrow monocyte cells
- to stimulate osteoclast differentiation in non-adherent hematopoietic cell
- for the generation of blood-derived stem cells
| [Uses]
Antineoplastic; anti-infective
growth factor that acts on both progenitor and mature
cells of the macrophage line. | [General Description]
M-CSF (macrophage colony-stimulating factor) is a potent hematopoietic factor produced by a variety of cells including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. The protein works through its receptor CSF1R (colony stimulating factor 1 receptor). The human is reactive in murine systems, but the murine molecule exhibits no activity on human cells. Recombinant murine M-CSF is a 36.4kDa homodimeric protein containing two 156 amino acid polypeptide subunits. | [Biochem/physiol Actions]
M-CSF (macrophage colony-stimulating factor) is a key regulator of cellular proliferation, differentiation, and survival of blood monocytes, tissue macrophages and their progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness, and male and female fertility. M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis. It facilitates hematopoietic recovery after bone marrow transplantation. M-CSF also works as a pleiotropic growth factor and plays a crucial role in reproduction and organogenesis. Absence of it can result in reduced growth, neurological and reproductive problems, developmental defects in the mammary gland, bone and pancreas. M-CSF is also involved in the pathogenesis of cancer. |
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| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
ACROBiosystems
|
| Tel: |
18514007688 |
| Website: |
www.acrobiosystems.cn/?utm_source=chemical book&utm_medium=cpy&utm_campaign=chemical book official web site |
|